Search for dissertations about: "beta cells"

Showing result 6 - 10 of 630 swedish dissertations containing the words beta cells.

  2. 6. Studies of individual pancreatic -cells : Electrophysiological analysis of rhythmic behaviour and development of new techniques

    Author : Staffan Dryselius; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Diabetes; pancreatic beta-cells; insulin release; signal transduction; cytoplasmic calcium; oscillations; patch clamp; ATP-regulated potassium channels; voltage-dependent calcium channels; metabolism; calcium ion; strontium ion; manganese ion; wavelets; de-noising; pattern recognition; superfusion; solution changes; microscopic labelling; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Abstract : The insulin concentration in blood varies periodically, which is believed to prevent down-regulation of the hormone receptors. Loss of the regular insulin oscillations is considered to be an early sign of developing diabetes. READ MORE

  4. 7. Hormone-Sensitive Lipase and Protein Kinase B; Molecular characterization in testis, adipose tissue and pancreatic beta cells

    Author : Lena Stenson; Signaltransduktionsforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; signal transduction; pancreas; beta cells; adipocyte; insulin; Akt; protein kinase B; spermatogenesis; cholesterol esterase; hormone-sensitive lipase; testis; cAMP; Proteins; enzymology; Proteiner; enzymologi;

    Abstract : Hormone-sensitive lipase (HSL) and protein kinase B (PKB) are enzymes that in different ways are associated with lipid metabolism. While HSL is the well-known lipolytic enzyme responsible for hydrolysis of stored triacylglycerols in adipose tissue, PKB is a recently identified serine/threonine protein kinase, ubiquitously expressed and involved in signal transduction pathways induced by insulin and growth factors. READ MORE

  5. 8. Regulation of Hematopoietic Stem Cells

    Author : Emma Rörby; Avdelningen för molekylärmedicin och genterapi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoiesis; hematopoietic stem cells; hematopoietic stem cell expansion; cord blood; transforming growth factor beta; Smad signaling; pigment epithelium derived factor; CD9;

    Abstract : This thesis is about the regulation of hematopoietic stem cells (HSCs) that represent rare cells residing in the bone marrow (BM) of adults. They are multipotent cells that have the capacity to differentiate to all mature cells of the blood system and have the capacity to self-renew, i.e. generate new HSCs. READ MORE

  6. 9. The role of glial cells in alpha-synuclein pathology : Focus on degradation, cell-to-cell propagation and inflammation

    Author : Jinar Rostami; Anna Erlandsson; Martin Ingelsson; Joakim Bergström; Michael Heneka; Uppsala universitet; []
    Keywords : Parkinson’s disease; alpha-synuclein; amyloid-beta; astrocytes; microglia; tunneling nanotubes; antigen presentation; T cells; glial crosstalk; degradation; KYP-2407; Medicinsk vetenskap; Medical Science;

    Abstract : Growing evidence emphasizes the role of astrocytes and microglia in Parkinson’s disease (PD) and Alzheimer’s disease (AD). Yet, little is known about their impact on specific disease processes and if their involvement is beneficial or detrimental. READ MORE

  7. 10. Properties of Endothelium and its Importance in Endogenous and Transplanted Islets of Langerhans

    Author : Åsa Johansson; Per-Ola Carlsson; JanOve Sehlin; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; islet transplantation; endothelial cells; engraftment; beta cells; Diabetology; Diabetologi; Medical Cell Biology; medicinsk cellbiologi;

    Abstract : Transplantation of insulin producing cells is currently the only cure for type 1 diabetes. However, even though the Edmonton protocol markedly increased the success rate of pancreatic islet transplantation, the long term insulin independence is still very poor. An adequate engraftment is critical for islet graft survival and function. READ MORE