Search for dissertations about: "beta lactamases"

Showing result 1 - 5 of 20 swedish dissertations containing the words beta lactamases.

2. 1. Enterobacteriaceae Producing Extended-Spectrum Beta-Lactamases : Aspects of Detection, Epidemiology and Control

   Author : Birgitta Lytsy; Åsa Melhus; Dan Andersson; Håkan Hanberger; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Extended-spectrum beta-lactamase; ESBL; pulse-field gel elctrophoresis; typing methods; infection control; typningsmetoder; vårdhygien; Bacteriology; Bakteriologi; Clinical Bacteriology; Klinisk bakteriologi;

   Abstract : Enterobacteriaceae belong to the normal enteric flora in humans and may cause infections. Escherichia coli is the leading urinary tract pathogen with septicaemic potential, whereas Klebsiella pneumoniae causes opportunistic infections and often outbreaks in hospital settings. READ MORE

4. 2. Multidrug-Resistant Escherichia coli and Klebsiella pneumoniae : Treatment, Selection and International Spread

   Author : Thomas Tängdén; Otto Cars; Anders Johansson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Escherichia coli; Klebsiella pneumoniae; extended-spectrum beta-lactamases; carbapenemases; metallo-beta-lactamases; synergy; antibiotic interventions;

   Abstract : The prevalence of Escherichia coli and Klebsiella pneumoniae producing extended-spectrum beta-lactamases (ESBLs) and carbapenemases is increasing worldwide. Therapeutic options for infections with these bacteria are limited not only by the production of ESBLs and carbapenemases, which confer resistance to cephalosporins and carbapenems, but also by frequent co-resistance to other antibiotics. READ MORE

5. 3. Carriage of ESBL (extended spectrum beta-lactamases)-producing bacteria : knowledge, emotional impact and risk assessment

   Author : Susanne Wiklund; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Extended-spectrum beta-lactamases;

   Abstract : Antibiotic-resistant bacteria, such as ESBL-producing Enterobacteriaceae, have become a growing public health threat. The overall aim of this thesis was to explore how the increasing prevalence of ESBL-producing bacteria affects different groups among the Swedish population. READ MORE

6. 4. Extended-spectrum beta-lactamase producing Enterobacteriaceae : aspects on detection, epidemiology and multi-drug resistance

   Author : Maria Tärnberg; Lennart Nilsson; Hans-Jürg Monstein; Håkan Hanberger; Kristian Riesbeck; Linköpings universitet; []
   Keywords : ;

   Abstract : Beta-lactam antibiotics are the largest and most commonly used group of antimicrobial agents in Sweden as well as world-wide. They show very good tolerability and many of the drugs can be administrated orally. READ MORE

7. 5. β-lactam combinations against multidrug-resistant Enterobacterales : Exploring combination effects and resistance development

   Author : Lisa Allander; Thomas Tängdén; Linus Sandegren; Pernilla Lagerbäck; Arnfinn Sundsfjord; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gram-negative bacteria; antibiotic combination therapy; antibiotic resistance; beta-lactams; beta-lactamase inhibitors; Infektionssjukdomar; Infectious Diseases;

   Abstract : The β-lactam antibiotics are a cornerstone in treating bacterial infections, but the increasing prevalence of antibiotic resistance worldwide threatens their effectiveness. The main driver of β-lactam resistance is the production of β-lactamases, which are bacterial enzymes that inactivate the antibiotic. READ MORE