Search for dissertations about: "beta tubulin III"

Showing result 1 - 5 of 6 swedish dissertations containing the words beta tubulin III.

  2. 1. EMBRYONIC GLIA AND FOREBRAIN NEUROGENESIS; in vitro generation and differentiation of telencephalic neurons

    Author : Charlotta Skogh; Neurobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; beta tubulin III; GFAP; RC2; Neurology; neuropsychology; neurofysiologi; DARPP-32; retinoic acid; serum; EGF; co-culture; cell culture; striatum; LGE; progenitor; precursor; radial glia; region specific; development; CNS; mouse; human; neurophysiology; Neurologi; neuropsykologi;

    Abstract : The current thesis is aimed to increase our understanding of the generation and differentiation of telencephalic neurons, with emphasis on the role of glial cells in these processes. Using in vitro methods we have studied the role of glial cells in neurogenesis, inheritance of genetic regional specification, and influence on differentiation of neurons. READ MORE

  4. 2. The N-methyl-D-aspartate receptor subunit NR3A : cloning, expression and interacting proteins

    Author : Maria Eriksson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : This thesis focuses on the subunit NR3A, which together with subunits NR1, NR2A-NR2D and NR3B builds the excitatory glutamate receptor N-methyl-D-aspartate (NMDA). The receptor is most likely a tetramer, containing at least one NR1, probably two NR2 and sometimes one NR3 subunit. READ MORE

  5. 3. Wnt signaling in early brain development and disease

    Author : Panagiotis Papachristou; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Wnt/Planar Cell Polarity (PCP) signaling is involved in many cellular processes throughout the development of the embryo. These include control of proliferation, differentiation, migration and cell fate decisions. Deregulation of Wnt/PCP signaling can lead to many developmental abnormalities and cancer. READ MORE

  6. 4. Integrin-interacting proteins in human cancer progression

    Author : Zhengwen An; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Integrins are the major transmembrane receptors for the extracellular matrix (ECM) which regulate a diverse array of cellular functions crucial to tumor cell migration, invasion, proliferation and survival. Integrins contact the ECM via their N-terminal extracellular domains and connect to the intracellular environment via the C-terminal cytoplasmic domains. READ MORE

  7. 5. Studies of presenilin function in neurodegeneration and in human embryonic CNS during development

    Author : Beata Kostyszyn; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Presenilin-1 (PS1) and -2 (PS2) gene mutations cause early onset familial Alzheimer's disease (FAD). Presenilins provide gamma-secretase activity for cleaving transmembrane proteins such as the amyloid precursor protein (APP), Notch receptors and ligands. READ MORE