Search for dissertations about: "beta-amyloid"

Showing result 6 - 10 of 34 swedish dissertations containing the word beta-amyloid.

2. 6. On the Nature of β-Amyloid at Synapses

   Author : Isak Martinsson; Experimentell demensforskning; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; synapses; APP knockout; beta-Amyloid;

   Abstract : Alzheimer’s disease is an aging related disorder of the mind, accountable for 60-80 percent of all cases of dementia. With its insidious progression and the decline of cognitive abilities, this disease is a major challenge for our society as a whole. READ MORE

4. 7. Multimodal Chemical Imaging of Amyloid Plaque Pathology in Alzheimer’s Disease

   Author : Wojciech Michno; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; beta-amyloid; electron microscopy; imaging mass spectrometry; lipids; luminescent conjugated oligothiophenes; matrix-assisted laser desorption ionization mass spectrometry MALDI-MS ; molecular imaging; nanoscale secondary ion mass spectrometry NanoSIMS ; neurodegeneration; peptides;

   Abstract : Alzheimer’s disease (AD) is the most common form of dementia. AD has been linked to the aggregation of amyloid beta (Aβ) peptides into extracellular deposits, Aβ plaques. These are also found in cognitively unimpaired amyloid-positive (CU-AP) individuals, but these Aβ plaques are primarily diffuse in structure. READ MORE

5. 8. Targeted Abeta proteomics - A tool to study the pathogenesis of Alzheimer’s disease

   Author : Erik Portelius; Göteborgs universitet; []
   Keywords : Alzheimer’s disease; Cerebrospinal fluid; Immunoprecipitation; Mass spectrometry; beta-amyloid;

   Abstract : Alzheimer’s disease (AD) is an age-related progressive neurodegenerative disorder of the central nervous system. Diagnosis and monitoring of sporadic AD has long depended on clinical examination of individuals with end-stage disease. READ MORE

6. 9. Inflammation and degeneration in neuropsychiatric SLE

   Author : Estelle Trysberg; Göteborgs universitet; []
   Keywords : NPSLE; CSF; IL-6; IL-8; MMP-9; NFL; GFAP; Tau; APP; beta-amyloid; IFN-gamma;

   Abstract : .... READ MORE

7. 10. Beta-amyloid, tau-protein and cystatin C in the pathophysiology of Alzheimer´s disease

   Author : Maj-Linda Selenica; Avdelningen för klinisk kemi och farmakologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurologi; neuropsykologi; neurofysiologi; neuropsychology; neurophysiology; Neurology; Medicine human and vertebrates ; Medicin människa och djur ; Clinical chemistry; Klinisk kemi; Kinase inhibitors; Tau protein; Cystatin C; Glycogen Synthase Kinase; Alzheimers Disease; Amyloid beta;

   Abstract : Alzheimer´s Disease (AD) is a progressive neurodegenerative dementia characterized by the extracellular accumulation of the beta-amyloid (Ab) peptide into plaques and intracellular phosphorylation and accumulation of tau protein into neurofibrillary tangles (NFT). Inflammation due to astrocytic and microglial activation is one of the ongoing processes in the disease giving rise to cytokine production and oxidative stress. READ MORE