Search for dissertations about: "beta-endorphin"
Showing result 6 - 10 of 10 swedish dissertations containing the word beta-endorphin.
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6. Migration of molecules in the brain : focus on the extracellular space and the cerebrospinal fluid
Abstract : Three different molecules and three different experimental models were used to study the migration of molecules in the rat brain: a neurotransmitter- dopamine, an extracellular market- mannitol, and a neuropeptide beta-endorphin. Two models in vivo were used to study the diffusion and migration of molecules: dual-probe rnicrodialysis in the striatum, and direct intrastriatal microinjections followed by cerebrospinal fluid sampling from the cisterna magna. READ MORE
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7. The Cerebrospinal Fluid in Severe Pain Conditions : Clinical, Pharmacological and Proteomic Aspects
Abstract : The treatment of both cancer pain and non-cancer chronic pain is still suboptimal. The overall aim of this PhD thesis was to conduct translational pain research at the interface between clinical pain medicine and the field of human proteomics, using the practice of intrathecal analgesia at our institution as a starting point. READ MORE
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8. Leukocyte activation in newborns in relation to prenatal stress
Abstract : The aim of this project is to describe the pattern of innate immunity responses at birth with focus on the recruitment of leukocytes such as eosinophils and neutrophils and their content of cathelicidin antimicrobial peptide LL-37 associated to different degrees of fetal stress and delivery modes. We know that delivery is associated to fetal stress including release of cortisol and cathecolamines. READ MORE
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9. Constitutive and TCDD-induced expression of Ah receptor responsive genes with special focus on the brain and pituitary
Abstract : The 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD) and related substances are ubiquitous environmental pollutants causing a number of pathological alterations, the most severe being progressive anorexia and body weight loss. The effects on body weight homeostasis suggest a possible involvement of the nervous system and neuroendocrine areas including the pituitary gland. READ MORE
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10. In vitro and postmortem studies of the brain opioid system : association to opiate dependence
Abstract : Opioids such as heroin are highly addictive illicit drugs. The μ opioid receptor (MOR) plays a central role in mediating the effects of opiates and related opioid. READ MORE