Search for dissertations about: "beta-lactams"

Showing result 1 - 5 of 8 swedish dissertations containing the word beta-lactams.

  1. 1. Haemophilus influenzae – typing, epidemiology and beta-lactam resistance

    Author : Viktor Månsson; Malmö Klinisk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; benzylpenicillin; beta-lactam resistance; beta-lactams; BLNAR; capsule typing; clonal; Haemophiilus influenzae; Hib; MALDI-TOF MS; MLST; NTHi; serotyping; virulence; epidemiology;

    Abstract : Haemophilus influenzae is a common cause of respiratory tract infections such as acute otitis media (AOM), exacerbations of chronic obstructive pulmonary disease (COPD) and pneumonia. The species is subdivided into encapsulated and non-encapsulated strains, designated type a-f and nontypeable H. influenzae (NTHi), respectively. READ MORE

  2. 2. β-lactam combinations against multidrug-resistant Enterobacterales : Exploring combination effects and resistance development

    Author : Lisa Allander; Thomas Tängdén; Linus Sandegren; Pernilla Lagerbäck; Arnfinn Sundsfjord; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gram-negative bacteria; antibiotic combination therapy; antibiotic resistance; beta-lactams; beta-lactamase inhibitors; Infektionssjukdomar; Infectious Diseases;

    Abstract : The β-lactam antibiotics are a cornerstone in treating bacterial infections, but the increasing prevalence of antibiotic resistance worldwide threatens their effectiveness. The main driver of β-lactam resistance is the production of β-lactamases, which are bacterial enzymes that inactivate the antibiotic. READ MORE

  3. 3. Enterobacteriaceae Producing Extended-Spectrum Beta-Lactamases : Aspects of Detection, Epidemiology and Control

    Author : Birgitta Lytsy; Åsa Melhus; Dan Andersson; Håkan Hanberger; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Extended-spectrum beta-lactamase; ESBL; pulse-field gel elctrophoresis; typing methods; infection control; typningsmetoder; vårdhygien; Bacteriology; Bakteriologi; Clinical Bacteriology; Klinisk bakteriologi;

    Abstract : Enterobacteriaceae belong to the normal enteric flora in humans and may cause infections. Escherichia coli is the leading urinary tract pathogen with septicaemic potential, whereas Klebsiella pneumoniae causes opportunistic infections and often outbreaks in hospital settings. READ MORE

  4. 4. Aspects of Bacterial Resistance to Silver

    Author : Susanne Sütterlin; Åsa Melhus; Björn Olsen; Roland Möllby; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antimicrobial resistance; Silver resistance; Clinical Bacteriology; Klinisk bakteriologi;

    Abstract : Bacterial resistance to antibiotics has increased rapidly within recent years, and it has become a serious threat to public health. Infections caused by multi-drug resistant bacteria entail higher morbidity, mortality, and a burden to health care systems. READ MORE

  5. 5. Haemophilus influenzae-induced acute otitis media. Aspects of virulence and protection in an animal model

    Author : Åsa Melhus; Malmö Klinisk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bacteriology; Microbiology; conjugate vaccine; protection; virulence; acute otitis media; Haemophilus influenzae; animal model; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : Acute otitis media (AOM) is the most common illness diagnosed during early childhood. One of the major etiologic agents is Haemophilus influenzae. Apart from AOM, this organism can cause a broad range of infectious diseases such as meningitis, epiglottitis, arthritis, and pneumonia. Despite the importance of H. READ MORE