Search for dissertations about: "bile acids"

Showing result 1 - 5 of 97 swedish dissertations containing the words bile acids.

  1. 1. Cytochrome P450 Enzymes in Bile Acid Biosynthesis and Fatty Acid Metabolism Studies on Members of the Porcine CYP4A and CYP8B Subfamilies

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Kerstin Lundell; Kjell Wikvall; Ronnie Hansson; Stefan Alexson; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biochemistry; cytochrome P450; bile acids; fatty acids; CYP4A; CYP8B; genome; porcine; hyocholic acid; Farmaceutisk biokemi; PHARMACY Pharmaceutical biochemistry; FARMACI Farmaceutisk biokemi; farmaceutisk biokemi; Pharmaceutical Biochemistry;

    Abstract : The present investigation is devoted to studies on porcine members of the cytochrome P450 4A (CYP4A) and CYP8B1 subfamilies, which are involved in bile acid biosynthesis and fatty acid metabolism. Hyocholic acid is considered to fulfil the requirements for trihydroxy bile acids in the domestic pig (Sus scrofa) in the absence of cholic acid. READ MORE

  2. 2. Regulation of bile acids by prebiotic food components : Studies in rat caecum and in serum of mice and humans

    University dissertation from Department of Food Technology, Lund University

    Author : Tannaz Ghaffarzadegan; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bile acids; Dietary fibre; Fat; Pectin; Guar gum; Barley; Lingonberry; Turmeric; Short-chain fatty acids; Gut microbiota; Caecum; Serum; Rat; Mice; Humans; GC-FID; UHPLC-MS;

    Abstract : Bile acids (BA) are formed from cholesterol in the liver and, apart from being part of fat digestion, they also act as signalling molecules in several health-related physiological processes. BA composition is regulated by gut microbiota as well as dietary fibre (DF) and fat in the diet. READ MORE

  3. 3. Gut microbial regulation of bile acid metabolism and signaling

    University dissertation from Department of Food Technology, Lund University

    Author : Sama I. Sayin; Göteborgs universitet.; Gothenburg University.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Gut Microbiota; Bile Acids;

    Abstract : The collection of microbes in our gastrointestinal tract, the gut microbiota, is an environmental factor that has profound impact on host health and disease. Bile acids are endogenous cholesterol-derived molecules that can be modified by the gut microbiota and function as signaling molecules in regulation of host metabolic processes. READ MORE

  4. 4. On the role of bile acids in chronic diarrhoea

    University dissertation from Department of Food Technology, Lund University

    Author : Kjell-Arne Ung; Göteborgs universitet.; Gothenburg University.; [2001]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diarrhoea; bile acid malabsorption; steatorrhoea; collagenous colitis; lymphocytic colitis; cholestyramine; long-term; histopathology; symptoms; ileal resection;

    Abstract : Bile acids which promote lipid absorption are actively reabsorbed in the distal ileum. Bile acid malabsorption (BAM) and microscopic colitis (lymphocytic and collagenous) are both associated with chronic watery diarrhoea. READ MORE

  5. 5. Bile Acid Induced Diarrhoea Pathophysiological and Clinical Aspects

    University dissertation from Department of Food Technology, Lund University

    Author : Antal Bajor; Göteborgs universitet.; Gothenburg University.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diarrhoea; bile acid transport; bile acid synthesis; 75SeHCAT reproducibility; C4; budesonide; collagenous colitis; in vitro; malabsorption; ASBT; intestinal secretion; potential difference; manometry;

    Abstract : A common cause for referral to gastroenterologists is chronic watery diarrhoea. Approximately 40% of these patients have idiopathic bile acid malabsorption (BAM) ? a condition with unknown aetiology. The 75SeHCAT test, which correlates inversely with faecal excretion and hepatic synthesis of bile acids, is used to diagnose BAM. READ MORE