Search for dissertations about: "biliary lipids"

Showing result 1 - 5 of 6 swedish dissertations containing the words biliary lipids.

  2. 1. Early steps of Eicosanoid precursor absorption and tissue distribution

    Author : Tor Melin; Lund Medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lipids; mebran; steroider; Lipider; steroids; membranes; Gastro-enterology; Gastroenterologi;

    Abstract : Eicosanoids are important for a wide range of physiological and pathophysiological processes.How their essential fatty acid precursors are absorbed and tissue distributed is not well charactherized. When given orally to rats, arachidonic acid (20:4) was retained in the small intestine to a larger extent than linoleic acid (18:2). READ MORE

  4. 2. Crohn's disease in Stockholm County : epidemiological panorama and associated gallstone disease

    Author : Annika Lapidus; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Bile acid; biliary lipids; bilirubin; cholesterol; colon; Crohn s disease; epidemiology; gallstone; ileal resection; incidence; prevalence; prognosis.;

    Abstract : Crohn's disease is a chronic inflammatory bowel disease of obscure etiology, affecting any part of the gastrointestinal tract but the ileocaecal region in particular. The annual incidence has gradually been increasing, and the clinical pattern has changed; a shift towards colorectal involvement as well as an increasing number of elderly patients has been observed. READ MORE

  5. 3. On the regulation of hepatic cholesterol and bile acid metabolism in gallstone patients

    Author : Carl-Gustaf Hillebrant; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Bile acid synthesis; biliary lipids; cholesterol synthesis; cholesterol 7a-hydroxylase; cholesterol synthesis inhibitor; chenodeoxycholic acid; cholestyramine; 7a-hydroxy-4-cholesten-3-one; HMG CoA reductase; lathosterol; lipoproteins; lithocholic acid; plasma apheresis; ursodeoxycholic acid;

    Abstract : The liver plays an important role in the regulation of cholesterol homeostasis, therefore also in the pathogenesis of arteriosclerosis and gallstone disease. The quantitatively most important way by which cholesterol is removed from the human body is via the bile, either as free cholesterol or after transformation to bile acids. READ MORE

  6. 4. Studies on the effects of thyroid hormone on cholesterol and lipoprotein metabolism

    Author : Ylva Bonde; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Elevated plasma lipids, particularly cholesterol within low density lipoproteins, is an important risk factor for developing atherosclerosis which can cause angina pectoris, myocardial infarction, and stroke. Thyroid hormone (TH) has a strong influence on lipid metabolism and the aim of this thesis was to gain more insight into how TH modulates cholesterol and lipoprotein metabolism. READ MORE

  7. 5. Understanding the molecular mechanisms of bile acid receptor activation for the treatment of human liver disease

    Author : Samer Al-Dury; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicinska sjukdomar; Gastroenterologi och hepatologi; FXR; IBAT; Gallsyror; Obesitas; Gallstenar;

    Abstract : Farnesoid X receptor (FXR) is a nuclear transcription factor that is activated by bile acids and regulates bile acid homeostasis, glucose and lipid metabolism. FXR activation by a ligand has been identified as a therapeutic modality for a range of liver and metabolic diseases. READ MORE