Search for dissertations about: "binding specificities"

Showing result 1 - 5 of 62 swedish dissertations containing the words binding specificities.

2. 1. Novel binding specificities engineered into the scaffold of a carbohydrate binding module

   Author : Lavinia Cicortas Gunnarsson; Institutionen för immunteknologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bioteknik; Biotechnology; carbohydrate binding module; binding specificity; selection; combinatorial library; scaffold; protein engineering;

   Abstract : The growing field of biotechnology is in constant need of proteins that can function as recognition tools for separational, analytical and therapeutic purposes. Different molecular engineering approaches are applied on natural proteins in order to create variants with desired properties. READ MORE

4. 2. Sialic acid-dependent binding specificities of Helicobacter pylori and influenza virus. Importance of different parts of the binding sequences

   Author : Petra Johansson; Göteborgs universitet; []
   Keywords : sialic acid; carbohydrates; Helicobacter pylori; influenza virus; binding specificities; glycosphingolipids;

   Abstract : Many viruses and bacteria adhere to host cell glycoconjugates in a specific manner, utilizing selected carbohydrate sequences. The aim of this work was to investigate at a molecular level the interactions of two important human pathogens, influenza virus and Helicobacter pylori, with sialylated carbohydrate structures. READ MORE

5. 3. Determination of transcription factor binding specificities

   Author : Arttu Jolma; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The term "genetic code" refers to the way in which the information encoded in nucleic acids is converted into the amino-acid sequence of proteins. There is however also a second genetic code, one that is used by the cells to read the blueprints of the entire organism. READ MORE

6. 4. Computational Prediction Models for Proteolytic Cleavage and Epitope Identification

   Author : Liwen You; Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; medical informatics; biomathematics biometrics; Bioinformatics; SVM; sequence analysis; rule extraction; protease-peptide interaction; OSRE; MHC; immunology; HIV; hierarchical method; HCV; Gaussian process; false positive; epitope; cleavage specificity; cleavage prediction; binding affinity; caspase; Bioinformatik; medicinsk informatik; biomatematik; Computer science; numerical analysis; systems; control; Datalogi; numerisk analys; system; kontroll; Binding affinity; Bioinformatics;

   Abstract : The biological functions of proteins depend on their physical interactions with other molecules, such as proteins and peptides. Therefore, modeling the protein-ligand interactions is important for understanding protein functions in different biological processes. READ MORE

7. 5. Fungal Lectins. Molecular structure and function of a member of a novel lectin family

   Author : Stefan Rosén; Biologiska institutionen; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; possible functions; expression; localization; binding specificities; primary and secondary structure; Agaricus bisporus; Arthrobotrys oligospora; Fungi; novel lectin family; Biology; Biologi;

   Abstract : Lectins defined as non-enzyme, non-immunoglobulin carbohydrate binding proteins, have been found in a wide variety of viruses, bacteria, fungi, plants and animals. Although lectins have been purified from more than 60 different species of fungi, the structure and biological functions of these proteins are not well known. READ MORE