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Showing result 1 - 5 of 62 swedish dissertations matching the above criteria.
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1. Novel binding specificities engineered into the scaffold of a carbohydrate binding module
Abstract : The growing field of biotechnology is in constant need of proteins that can function as recognition tools for separational, analytical and therapeutic purposes. Different molecular engineering approaches are applied on natural proteins in order to create variants with desired properties. READ MORE
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2. Sialic acid-dependent binding specificities of Helicobacter pylori and influenza virus. Importance of different parts of the binding sequences
Abstract : Many viruses and bacteria adhere to host cell glycoconjugates in a specific manner, utilizing selected carbohydrate sequences. The aim of this work was to investigate at a molecular level the interactions of two important human pathogens, influenza virus and Helicobacter pylori, with sialylated carbohydrate structures. READ MORE
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3. Determination of transcription factor binding specificities
Abstract : The term "genetic code" refers to the way in which the information encoded in nucleic acids is converted into the amino-acid sequence of proteins. There is however also a second genetic code, one that is used by the cells to read the blueprints of the entire organism. READ MORE
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4. Computational Prediction Models for Proteolytic Cleavage and Epitope Identification
Abstract : The biological functions of proteins depend on their physical interactions with other molecules, such as proteins and peptides. Therefore, modeling the protein-ligand interactions is important for understanding protein functions in different biological processes. READ MORE
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5. Fungal Lectins. Molecular structure and function of a member of a novel lectin family
Abstract : Lectins defined as non-enzyme, non-immunoglobulin carbohydrate binding proteins, have been found in a wide variety of viruses, bacteria, fungi, plants and animals. Although lectins have been purified from more than 60 different species of fungi, the structure and biological functions of these proteins are not well known. READ MORE