Search for dissertations about: "bioanalytical chemistry"

Showing result 1 - 5 of 24 swedish dissertations containing the words bioanalytical chemistry.

2. 1. Miniaturised Bioanalytical Chemistry in Acoustically Levitated Droplets

   Author : Sabina Santesson; Centrum för analys och syntes; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; Analytisk kemi; protein crystallisation; affinity two-phase partitioning; single cell analysis; bioanalytical chemistry; airborne chemistry; levitated droplets; Miniaturisation; acoustic levitation;

   Abstract : Fuelled by the current demands of the biological sciences, there is today a growing interest in microscale analysis. Miniaturisation of analytical instruments has become a long-standing trend. Miniaturisation offers several advantages, including rapid separation times, high performance and throughput, reduced costs, etc. READ MORE

4. 2. Bioanalytical separation using capillary electrophoresis : Applications with microbubbles and proteins

   Author : Leila Josefsson; Åsa Emmer; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Background electrolyte; capillary electrophoresis; contrast agents; electroosmotic flow; ethylammonium nitrate; ionic liquids; microbubbles; particles; polyvinyl alcohol microbubbles; and separation; Kemi; Chemistry;

   Abstract : In this thesis the possibilities of using capillary electrophoresis as a separation technique for analysis of proteins and microbubbles is presented.A complete analytical process consists of five necessary steps of which one is the actual analysis step. For this step a suitable analytical technique is needed. READ MORE

5. 3. Development and Validation of Bioanalytical Methods : Application to Melatonin and Selected Anti-Infective Drugs

   Author : Susanne Römsing; Yngve Bergqvist; Åsa Emmer; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; african trypanosomiasis; melatonin; malaria; antiretroviral drugs; lumefantrine; tafenoquine; lamivudine; nevirapine; zidovudine; sampling paper; dried blood spots; capillary blood; antimalarial drugs; solid-phase extraction; liquid chromatography; Chemistry; Kemi; Analytical Chemistry; Analytisk kemi;

   Abstract : This thesis describes bioanalytical methods for measuring melatonin and some anti-infective drugs in biological fluids. Solid-phase extraction (SPE) or protein precipitation was used for enrichment and purification of the analytes and Liquid Chromatography (LC) was used to analyze the samples. READ MORE

6. 4. Electrophoretic focusing in microchannels combined with mass spectrometry : Applications on amyloid beta peptides

   Author : Saara Mikkonen; Åsa Emmer; Johan Jacksén; Tapio Kotiaho; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; amyloid beta; computer simulation; electrophoresis; electrospray ionization; isoelectric focusing; isotachophoresis; MALDI; mass spectrometry; microchannel; microchip; nano-electrospray ionization; preconcentration; separation; Kemi; Chemistry;

   Abstract : Analysis of low-abundance components in small samples remains a challenge within bioanalytical chemistry, and new techniques for sample pretreatments followed by sensitive and informative detection are required. In this thesis, procedures for preconcentration and separation of proteins and peptides in open microchannels fabricated on silicon microchips are presented. READ MORE

7. 5. Methods for structural studies of an antibody, screening metabolites in rat urine and analysis of spent cell cultivation media using LC/ESI-MS and chemometrics

   Author : Leila Zamani; Sven P. Jacobsson; Jonas Bergqvist; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Screening; Fingerprinting; metabolomics; Protein drugs; Mammalian Cell lines; LC ESI-MS; chemometrics; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

   Abstract : This thesis describes bioanalytical methods for generating fingerprints of biological systems for extracting relevant information with (protein) drugs in focus. Similarities and differences between samples can reveal the hidden relevant information, which can be used to optimize the production and facilitate the quality control of such protein drugs during their development and manufacture. READ MORE