Search for dissertations about: "biobank research"

Showing result 1 - 5 of 49 swedish dissertations containing the words biobank research.

2. 1. Biobank Research : Individual Rights and Public Benefit

   Author : Joanna Stjernschantz Forsberg; Stefan Eriksson; Mats G. Hansson; Angus Dawson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biobank; Ethics; Consent; Returning results; Individual rights; Public good; Medicinsk vetenskap; Medical Science;

   Abstract : The aim of this thesis is to investigate the relationship between individuals and society in the context of healthcare and medical research, more specifically concerning the rights and duties of individuals in regard to biobank-based research. My starting point is that we all have a strong vested interest in improved healthcare, and therefore the possibilities to conduct important research should be optimized. READ MORE

4. 2. Trust in Biobank Research : Meaning and Moral Significance

   Author : Linus Johnsson; Mats G. Hansson; Gert Helgesson; Stefan Eriksson; Berge Solberg; Uppsala universitet; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biobank; biobank research; bioethics; biobank ethics; research ethics; trust; trustworthiness; moral responsibility; informed consent; ethics review; ethics guidelines; Bioetik; Bioethics;

   Abstract : What role should trust have in biobank research? Is it a scarce resource to be cultivated, or does its moral significance lie elsewhere? How does it relate to the researcher’s individual responsibility?In this thesis I draw four general conclusions. First, trust is still very much present in at least some biobanking settings, notably in Sweden, but possibly also internationally. READ MORE

5. 3. Usefulness of archival biobank samples for genetic epidemiologic studies

   Author : Malin Sjöholm; Malmö Klinisk mikrobiologi; []
   Keywords : formailn-fixed paraffin-embedded tissue; biobank; serum; dried blood spots; plasma; archival samples;

   Abstract : Sweden has a long history of maintaining population-based registries and biobanks. This has resulted in large sample collections with long follow-up and large numbers of prospectively occurring disease endpoints providing an extensive resource for genetic research. READ MORE

6. 4. Modeling glioblastoma heterogeneity to decipher its biology

   Author : Yuan Xie; Lene Uhrbom; Massimo Squatrito; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioblastoma multiforme; biobank; GBM cells; cell of origin; LGR5; OPCs;

   Abstract : Glioblastoma multiforme (GBM) is the most common and lethal form of primary brain tumor that mainly affects adults. GBM displays remarkable intra- and inter-tumoral heterogeneity and contains a subpopulation of cells named glioma stem cells that is believed to be responsible for tumor maintenance, progression and recurrence. READ MORE

7. 5. Depression : genetic, epigenetic and DNA biobank studies

   Author : Philippe A Melas; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Depression is a disease that has an estimated lifetime prevalence of ~15% and a heritability of ~36%. There is support for a heterogeneous etiology of depression, which includes: a) numerous genetic loci, b) various epigenetic contributors, and c) different environmental risk factors. READ MORE