Search for dissertations about: "biochemistry"
Showing result 21 - 25 of 1831 swedish dissertations containing the word biochemistry.
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21. Structural and biochemical studies of phage P2 DNA-binding proteins and human tetraspanins
Abstract : Biochemical studies of proteins are crucial for a more detailed view of the world around us. The focus of biochemical studies can vary, from a complex mammalian system to a more simple viral entity, but the same methods and principles apply. In biochemistry one rely on both in vitro and in vivo analyses to understand biological processes. READ MORE
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22. The birth of the hydrogenase : Studying the mechanism of [FeFe] hydrogenase maturation
Abstract : The [FeFe] hydrogenases are ancient metalloenzymes that catalyse the reversible interconversion between protons, electrons and molecular hydrogen. Despite the large structural variability within the [FeFe] hydrogenase family, the active site, the so called “H-cluster” is present in every representative. READ MORE
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23. Discovery and evaluation of direct acting antivirals against hepatitis C virus
Abstract : Until recently, the standard therapy for hepatitis C treatment has been interferon and ribavirin. Such treatment has only 50% efficacy and is not well tolerated. The emergence of new drugs has increased the treatment efficacy to 90%. READ MORE
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24. Structural studies on the integral membrane protein, ubiquinol oxidase from Escherichia coli
Abstract : Heme-copper oxidases are redox-driven proton pumps that couple the reduction of molecular oxygen to water with the vectorial translocation of protons across the membrane. The proton gradient generated by heme-copper oxidases and the other members of the aerobic respiratory chain is ultimately used to drive the synthesis of ATP. READ MORE
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25. Folding and interaction studies of subunits in protein complexes
Abstract : Proteins function as worker molecules in the cell and their natural environment is crowded. How they fold in a cell-like environment and how they recognize their interacting partners in such conditions, are questions that underlie the work of this thesis. READ MORE