Search for dissertations about: "biokemi med inriktning mot bioinformatik"
Showing result 11 - 15 of 39 swedish dissertations containing the words biokemi med inriktning mot bioinformatik.
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11. Intrinsic disorder and tandem repeats - match made in evolution : Computational studies of molecular evolution
Abstract : Proteins are both the building blocks and workers of the cell, carrying out most of the important functions. For a long time, their structure has been regarded as the primary factor for their function, but intrinsically disordered proteins demonstrate an alternative to this paradigm. READ MORE
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12. From Sequence to Structure : Using predicted residue contacts to facilitate template-free protein structure prediction
Abstract : Despite the fundamental role of experimental protein structure determination, computational methods are of essential importance to bridge the ever growing gap between available protein sequence and structure data. Common structure prediction methods rely on experimental data, which is not available for about half of the known protein families. READ MORE
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13. Predicting the route: from protein sequence to sorting in eukaryotic cell
Abstract : Proteins need to be localised in the correct compartment of a eukaryotic cell to function correctly. Therefore, a protein needs to be transported to the right location. Specific signals present in the protein sequence direct proteins to different subcellular localisations. READ MORE
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14. Unlocking protein sequences : Advances in protein structure and ligand-binding site prediction
Abstract : The protein sequence determines how it will fold into its unique three-dimensional structure. Once folded, proteins perform their functions by interacting with other proteins or molecules called ligands within the cell. Experimental determination of protein structure and function is tedious. READ MORE
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15. Calculations of Reaction Mechanisms and Entropic Effects in Enzyme Catalysis
Abstract : Ground state destabilization is a hypothesis to explain enzyme catalysis. The most popular interpretation of it is the entropic effect, which states that enzymes accelerate biochemical reactions by bringing the reactants to a favorable position and orientation and the entropy cost of this is compensated by enthalpy of binding. READ MORE