Search for dissertations about: "biokemisk farmakologi"

Showing result 1 - 5 of 7 swedish dissertations containing the words biokemisk farmakologi.

  1. 1. Cannabinoids as modulators of cancer cell viability, neuronal differentiation, and embryonal development

    University dissertation from Umeå : Umeå universitet

    Author : Sofia Gustafsson; Umeå universitet.; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cannabinoids; cell viability; neuronal differentiation; colorectal cancer; chick embryo; biokemisk farmakologi; biokemisk farmakologi; Toxicology; toxikologi;

    Abstract : Cannabinoids (CBs) are compounds that activate the CB1 and CB2 receptors. CB receptors mediate many different physiological functions, and cannabinoids have been reported to decrease tumor cell viability, proliferation, migration, as well as to modulate metastasis. READ MORE

  2. 2. Novel Fatty Acid Dioxygenases of Human and Plant Pathogenic Fungi Studies by Gene Deletion and Expression

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Fredrik Jernerén; Uppsala universitet.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; aspergilli; dioxygenase; oxygenase; Magnaporthe oryzae; Gaeumannomyces graminis; Lasiodiplodia theobromae; jasmonic acid; linoleate diol synthase; cyclooxygenase; prostaglandin H synthase; cytochrome P450; oxylipin; hydroperoxide isomerase; allene oxide synthase; PHARMACY Pharmaceutical pharmacology; FARMACI Farmaceutisk farmakologi; Biochemical Pharmacology; Biokemisk farmakologi;

    Abstract : The dioxygenase-cytochrome P450 fusion proteins (DOX-CYP) comprise a heme-containing enzyme family that shares structural and catalytic properties with mammalian prostaglandin H (PGH) synthases. 7,8-Linoleate diol synthase (7,8-LDS) of Gaeumannomyces graminis was first characterized, and DOX-CYP enzymes are of mechanistic and biological interest. READ MORE

  3. 3. Mass Spectrometric Analysis of Oxylipins Application to Cytochrome P450-Dependent Metabolism

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Tomas Nilsson; Uppsala universitet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; epoxyalcohols; fatty acids; hydroperoxides; electrospray ionization; ichthyosis; CYP4; linear ion trap; fragmentation mechanism; PHARMACY Pharmaceutical pharmacology; FARMACI Farmaceutisk farmakologi; Biochemical Pharmacology; Biokemisk farmakologi;

    Abstract : Cytochrome P450 (CYP) family 4 constitutes monoxygenases responsible for hydroxylation of fatty acids and other lipids. For example, CYP4F3 metabolizes leukotrienes and CYP4F8 prostaglandin H. Importantly, six of the twelve CYP4 enzymes are orphans, i.e. READ MORE

  4. 4. Beta-Glycosidases from Hyperthermophiles as Biocatalysts

    University dissertation from Therese Hansson, Dept. of Biotechnology, Lund University

    Author : Therese Hansson; Lunds universitet.; Lund University.; [2002]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Bioteknik; Biochemical technology; Biokemisk teknik; Proteins; enzymology; Proteiner; enzymologi; Biotechnology; high temperatures; water activity; activity; selectivity; hexanol; hexyl-b-glycoside; galacto-oligosaccharides; lactose; hyperthermostable b-glycosidase; hydrolysis; optimisation; transglycosylation;

    Abstract : The thesis concerns glycosyl transfer with use of b-glycosidases, most of them from hyperthermophilic organisms. Both optimisation of the reaction conditions and protein engineering in terms of site-directed mutagenesis were used to improve b-glycosidase-catalysed reactions. READ MORE

  5. 5. Lipases as Biocatalysts in Organic Media. Influence of Enzyme Preparation and Reaction Conditions on Activity and Selectivity

    University dissertation from Mattias Persson Sölvegatan 39, kemicentrum, Lunds universitet

    Author : Mattias Persson; Lunds universitet.; Lund University.; [2001]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biochemical technology; Bioteknik; Biotechnology; water activity; temperature; enantioselectivity; immobilisation; organic solvents; lyophilisation; Lipases; Accurel EP-100; Biokemisk teknik; Proteins; enzymology; Proteiner; enzymologi;

    Abstract : The discovery that enzymes can function in organic solvents has broadened the scope of biocatalysis, making enzymes highly useful tools for organic chemists. The widespread use of enzymes as catalysts in organic solvents has, however, been limited by the low activity obtained for enzymes in organic solvents compared to aqueous solutions. READ MORE