Search for dissertations about: "biologic"

Showing result 1 - 5 of 69 swedish dissertations containing the word biologic.

  1. 1. Photochromism - Logic and Biologic Approaches

    Author : Martin Hammarson; Chalmers University of Technology; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; DNA-binding; molecular logic; dithienylethene; photochromism; DNA; photoswitch; spiropyran;

    Abstract : Photochromism is the light-induced colour change of molecules called photo-chromic compounds. The isomerisation causes changes in the electronic properties of the molecules and rearrangements of bonds which can be used in many more applications than the observed colour change. READ MORE

  2. 2. Psoriasis in Sweden : observational studies from an epidemiological perspective

    Author : David Hägg; Marcus Schmitt-Egenolf; Anders Sundström; Marie Eriksson; Bernt Lindelöf; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psoriasis; Systemic treatments; Biologic treatments; PASI; DLQI; Register-based research; Dermatology and Venerology; dermatologi och venereologi;

    Abstract : Background: Psoriasis is a heterogeneous disease with several clinical manifestations; the symptoms are characterized by redness, scaliness and thickness of the skin. There are several treatment options available for psoriasis and patients with moderate to severe psoriasis generally need systemic agents. READ MORE

  3. 3. Biological Rhythms of Pancreatic Secretion in Young Pigs with empahasis to the time around weaning

    Author : Mary-Jane Sebabatso Thaela; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Volume; Ultradian; Protein; Pancreas; Pig; IRCT; Insulin; Infradian; Glucose; Circadian; Chymotrypsin; Biologic week and Half-week; Chronome; Animal physiology; Djurfysiologi;

    Abstract : When the time structure (chronome) of pancreatic secretion was studied after weaning in 5-week-old pigs, the zero-amplitude (no-rhythm) assumption was rejected for the about-weekly (circaseptan, CS) and about-half-weekly (circasemiseptan, CSS) chronome components. When the data were assessed individually on a day-to-day basis, a 24-hour component was suggested (P. READ MORE

  4. 4. Biological therapy in rheumatoid arthritis : epidemiological studies

    Author : Katerina Chatzidionysiou; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The landscape of RA treatment has unquestionably changed dramatically during the last decade. A deeper understanding of the pathophysiological and immunological mechanisms in RA, earlier and more aggressive treatment, and the development and introduction to daily clinical practice of a new class of antirheumatic drugs, the so-called biologic therapies, has contributed to this ‘revolution’. READ MORE

  5. 5. Pharmacometric Modeling in Rheumatoid Arthritis

    Author : Brigitte Lacroix; Lena Friberg; Mats Karlsson; Maria Laura Sargentini-Maier; Kosmas Kretsos; Ekaterina Gibiansky; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rheumatoid arthritis; PKPD; immunogenicity; ACR; IPPSE; certolizumab pegol;

    Abstract : Biologic therapies have revolutionized the treatment of rheumatoid arthritis, a common chronic inflammatory disease, mainly characterized by the chronic inflammation of the joints. The activity and progression of the disease are highly variable, both between subjects and between the successive assessments for the same subject. READ MORE