Search for dissertations about: "biologically based cancer growth models"

Found 3 swedish dissertations containing the words biologically based cancer growth models.

2. 1. Liver tumour promoting effects by polychlorinated biphenyls

   Author : Marie Haag Grönlund; Karolinska Institutet; Karolinska Institutet; []
   Keywords : tumour promotion; altered hepatic foci; rat liver; PCB; potency; TEF; interactions; antagonism; biologically based cancer growth models; TCDD;

   Abstract : PCBs cause a number of toxic effects and are present in a variety of biological samples including fish, meat and diary products. Cancer is a serious toxic effect by PCBs that has been observed in animal experiments but the knowledge about PCB induced carcinogenicity is still scarce. READ MORE

4. 2. The use of IGF-IR inhibitors in cancer therapy : a potential approach for sensitizing tumor cells to ionizing radiation

   Author : Daria Cosaceanu; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : This study focused on insulin-like growth factor I receptor (IGF-IR), considered as a promising therapeutic target for cancer treatment. We were in particular interested in the involvement of IGF-IR in tumor cells response to radiation and we tried to provide the rationale for a combined therapy of IFG4R inhibitors with radiation in order to improve the therapeutic outcome. READ MORE

5. 3. Mathematical Modelling of Cell Migration and Polarization

   Author : Adam Malik; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

   Abstract : Cell migration plays a fundamental role in both development and disease. It is a complex process during which cells interact with one another and with their local environment. Mathematical modelling offers tools to investigate such processes and can give insights into the underlying biological details, and can also guide new experiments. READ MORE