Search for dissertations about: "biomarkers of ageing"
Showing result 1 - 5 of 14 swedish dissertations containing the words biomarkers of ageing.
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1. Computational discovery of DNA methylation patterns as biomarkers of ageing, cancer, and mental disorders : Algorithms and Tools
Abstract : Epigenetics refers to the mitotically heritable modifications in gene expression without a change in the genetic code. A combination of molecular, chemical and environmental factors constituting the epigenome is involved, together with the genome, in setting up the unique functionality of each cell type. READ MORE
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2. Independent Ageing in Very Old Swedish Men
Abstract : Predictors for survival have been investigated thoroughly, but less is known about how to reach high age with preserved physical and cognitive function. These functions are crucial to stay independent in daily life, which is highly valued by the oldest old.This thesis was based on data from the Uppsala Longitudinal Study in Adult Men. READ MORE
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3. Determination of biomarkers for lipid peroxidation and oxidative stress : Development of analytical techniques and methods
Abstract : Oxidative stress can be defined as a state of disturbance in the pro-oxidant/antioxidant balance in favour of the former, leading to potential damage. Processes associated with oxidative stress involve reactive oxygen species and radicals and can result in elevated levels of oxidatively modified or toxic molecules that can cause cellular malfunction, and even cell death. READ MORE
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4. Chronic Systemic Inflammation, Body Composition and Physical Activity Behaviours in Older Adults
Abstract : Ageing is associated with a gradual physical decline accompanied by changes in body composition. The occurrence of a low-grade yet chronic state of systemic inflammation has gained interest for its potential consequences in the ageing process. READ MORE
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5. Reliability of visual assessment of medial temporal lobe atrophy
Abstract : Background: Medial temporal lobe atrophy (MTA) has been found to be an early sign of Alzheimer’s disease (AD). Visual assessment of MTA (vaMTA) is a rapid, cost-efficient and clinically adaptable visual interpretation method for rating MTA, based on coronal magnetic resonance imaging (MRI) scans. READ MORE