Search for dissertations about: "biomolecular detection"

Showing result 1 - 5 of 44 swedish dissertations containing the words biomolecular detection.

  1. 1. Detection of Biomolecules Using Volume-Amplified Magnetic Nanobeads

    Author : Teresa Zardán Gómez de la Torre; Maria Strømme; Peter Svedlindh; Mikkel Fougt Hansen; Uppsala universitet; []
    Keywords : ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; Magnetic biosensor; magnetic nanobeads; Brownian relaxation; padlock probe; rolling circle amplification; DNA detection; protein detection; Teknisk fysik med inriktning mot nanoteknologi och funktionella material; Engineering Science with specialization in Nanotechnology and Functional Materials;

    Abstract : This thesis describes a new approach to biomolecular analysis, called the volume-amplified magnetic nanobead detection assay (VAM-DNA). It is a sensitive, specific magnetic bioassay that offers a potential platform for the development of low-cost, easy-to-use diagnostic devices. READ MORE

  2. 2. Conjugated Polymers, Amyloid Detection and Assembly of Biomolecular Nanowires

    Author : Anna Herland; Olle Inganäs; Samuel I. Stupp; Linköpings universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; Conjugated Polymers; Amyloid Fibrils; Nanowires; Self-Assembly; Sensor; Amyloid Detection; Physics; Fysik;

    Abstract : The research field of conjugated polymers has grown due to the optical and electronic properties of the material, useful in applications such as solar cells and printed electronics, but also in biosensors and for interactions with biomolecules. In this thesis conjugated polymers have been used in two related topics; to detect conformational changes in proteins and to assemble the polymers with biomolecules into nanowires. READ MORE

  3. 3. Readout Strategies for Biomolecular Analyses

    Author : Jenny Göransson; Mats Nilsson; Charles Cantor; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Padlock probe; Selector probe; Rolling circle amplification; Single molecule detection; Amplified single molecule; Random array; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ;

    Abstract : This thesis describes three readout formats for molecular analyses. A common feature in all works is probing techniques that upon specific target recognition ideally results in equimolar amounts of DNA circles. These are then specifically amplified and detected using any of the techniques presented herein. READ MORE

  4. 4. Biomolecular Recognition Based on Field Induced Magnetic Bead Dynamics

    Author : Rebecca Stjernberg Bejhed; Peter Svedlindh; Klas Gunnarsson; Maria Strömme; Teresa Zardán Gómez de la Torre; Christer Johansson; Uppsala universitet; []
    Keywords : ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES; Magnetic biosensor; magnetic nanoparticle; DNA detection; Teknisk fysik; Engineering Science;

    Abstract : In this thesis, three different read-out techniques for biomolecular recognition have been studied. All three techniques rely on the change in dynamic behaviour of probe functionalised magnetic beads after binding to a biomolecular target complementary to the probe. READ MORE

  5. 5. Biosensor technology applied to hybridization analysis and mutation detection

    Author : Peter Nilsson; KTH; []
    Keywords : ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; biosensor; genosensor; surface plasmon resonance; hybridization; nucleic acids; oligonucleotide; mutation detection; mismatch discrimination; modular; Bioengineering; Bioteknik;

    Abstract : This thesis demonstrates the application of biosensor technology for molecular biology investigations, utilizing a surface plasmon resonance based optical device for mass sensitive detection of biomolecular interactions at a chipsurface. Oligonucleotide model systems were designed for analysis of the action of DNA manipulating enzymes. READ MORE