Search for dissertations about: "biomolecular detection"

Showing result 6 - 10 of 47 swedish dissertations containing the words biomolecular detection.

  2. 6. Hunting a Silent Killer. Biomolecular Approaches in Ovarian Cancer

    Author : Nicolai Arildsen; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ovarian cancer; Molecular biology; genetic variant; TP53 mutation; early detection; Drug Screening Assays; Antitumor; bioinformatics; next generation sequencing; NGS; prognostic and predictive biomarkers; ovarian clear cell cancer; high-grade serous ovarian cancer;

    Abstract : Ovarian cancer is a heterogeneous disease and recent advances in improving patient outcome havebeen limited. It is estimated that a woman’s risk of developing ovarian cancer during her lifetime is about 1 in 70, making it a frequently occurring cancer type in women. READ MORE

  4. 7. Biochip design based on tailored ethylene glycols

    Author : Andréas Larsson (Kaiser); Bo Liedberg; Tommy Nylander; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biosensor; biochip; poly ethylene glycol ; self-assembled monolayer; photopolymerisation; microarray; biomolecular interaction; explosives detection; Physics; Fysik;

    Abstract : Studies of biomolecular interactions are of interest for several reasons. Beside basic research, the knowledge gained from such studies is also very valuable in for example drug target identification. Medical care is another area where biomolecules may be used as biomarkers to aid physicians in making correct diagnosis. READ MORE

  5. 8. Protein Microarray Chips

    Author : Goran Klenkar; Bo Liedberg; Brian MacCraith; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Microarray; biosensor; biomolecular interaction; narcotics detection; imaging ellipsometry and surface plasmon resonance; Molecular biophysics; Molekylär biofysik;

    Abstract : Livet tas för givet av de flesta. Det finns däremot många som ägnar stora delar av sitt liv för att försöka lösa dess mysterier. En del av lösningen ligger i att förstå hur alla molekyler är sammanlänkade i det gigantiska nätverk som definierar den levande organismen. READ MORE

  6. 9. QCM-D – with focus on biosensing in biomolecular and cellular systems

    Author : Erik Nilebäck; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; QCM-D; biomolecular interactions; cell-surface interaction; glycosaminoglycans; viscoelasticity; cell morphology; Quartz crystal microbalance with dissipation monitoring; surface chemistry; protein conformation;

    Abstract : The high degree of complexity in biological systems is being investigated in greater and greater detail by increasingly sophisticated sensing approaches. The quartz crystal microbalance with dissipation monitoring (QCM-D) technique stands out in this context, by probing the viscoelastic properties at interfaces. READ MORE

  7. 10. Development and application of ultra-sensitive fluorescence spectroscopy and microscopy for biomolecular interaction studies

    Author : Lei Xu; Jerker Widengren; Gerhard Schütz; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; single molecule spectroscopy; fluorescence correlation spectroscopy; stimulated emission microscopy; cancer; biomolecular interaction; co-localization; Biological Physics; Biologisk fysik;

    Abstract : This thesis describes the development of sensitive and high-resolution fluorescence spectroscopic and microscopic techniques and their application to probe biomolecules and their interactions in solution, lipid membrane model systems and in cells. Paper I-IV are largely focused on methodological developments. READ MORE