Search for dissertations about: "biopharmaceutical thesis"

Showing result 1 - 5 of 25 swedish dissertations containing the words biopharmaceutical thesis.

  1. 1. China's Creation of Biopharmaceutical Drugs : Combining Political Steering, Military Research, and Transnational Networking

    University dissertation from Uppsala : Department of Business Studies, Uppsala University

    Author : Åse Linné; Uppsala universitet.; [2012]
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; innovation; biotechnology; China; resource interfaces; commerciali-zation; Chinese government; command network economy; biopharmaceutical drugs; military research;

    Abstract : Not only the Western world is focused on creating new innovations based on scientific discoveries; this is also the case in China where discoveries in biotechnology science are aimed at creating new biopharmaceutical drugs in order to create a future biotechnology industry and in the end generate economic growth. The focus to invest in high-tech industries such as biotechnology can be traced to the “open-door policy” issued in 1978 with the aim to modernize China and transform China into a “socialistic market economy. READ MORE

  2. 2. Systems Analysis of the Protein Secretory Pathway in Yeast and Human Cells

    University dissertation from Uppsala : Department of Business Studies, Uppsala University

    Author : Amir Feizi; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein production; flux balance analysis; biopharmaceutical; secretory pathway: secretome; recombinant protein; genome-scale modeling; systems biology;

    Abstract : The cell was discovered by Robert Hooke in 1665, later in nineteen century the cell theory was developed as all organisms are composed of one or more cells. Since then, many tools and experimental methods have been developed to dissect and characterize the cell components which resulted in established solid scientific fields such as biochemistry, molecular cell biology and genetics. READ MORE

  3. 3. Biopharmaceutical investigations of doxorubicin formulations used in liver cancer treatment Studies in healthy pigs and liver cancer patients, combined with pharmacokinetic and biopharmaceutical modelling

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Ilse R Dubbelboer; Uppsala universitet.; [2017]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; drug delivery system; in vivo release; PBPK modelling; hepatocellular carcinoma; doxorubicin; transarterial chemoembolization; drug disposition; Biofarmaci; Biopharmaceutics; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : There are currently two types of drug formulation in clinical use in the locoregional treatment of intermediate hepatocellular carcinoma (HCC). In the emulsion LIPDOX, the cytostatic agent doxorubicin (DOX) is dissolved in the aqueous phase, which is emulsified with the oily contrast agent Lipiodol® (LIP). READ MORE

  4. 4. Biopharmaceutical aspects of intestinal drug absorption Regional permeability and absorption-modifying excipients

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : David Dahlgren; Uppsala universitet.; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intestinal permeability; absorption-modifying excipients; Biofarmaci; Biopharmaceutics;

    Abstract : Before an orally administered drug reaches the systemic circulation, it has to dissolve in the intestinal fluids, permeate across the intestinal epithelial cell barrier, and pass through the liver. The permeation rate of drug compounds can be low and show regional differences.The thesis had two general aims. READ MORE

  5. 5. Modeling for Quality and Safety in Biopharmaceutical Production Processes

    University dissertation from Department of Chemical Engineering, Lund University

    Author : Karin Westerberg; Lunds universitet.; Lund University.; [2012]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Process modeling; chromatography; quality by design; robustness; process control;

    Abstract : Popular Abstract in Swedish Biotekniska läkemedel blir allt vanligare och behandlar några av våra viktigaste sjukdomar. Några exempel är insulin för diabetes, tillväxthormon, vacciner, och antikroppar som används i behandling av bland annat cancer, rheumatism och mag- tarmsjukdomar. READ MORE