Search for dissertations about: "biosynthetic engineering"

Showing result 1 - 5 of 17 swedish dissertations containing the words biosynthetic engineering.

  2. 1. Multidimensional engineering for the production of fatty acid derivatives in Saccharomyces cerevisiae

    Author : Yating Hu; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; protein engineering; Saccharomyces cerevisiae; fatty acid derivatives; metabolic engineering; tolerance; transporter;

    Abstract : Saccharomyces cerevisiae , also known as budding yeast, has been important for human society since ancient time due to its use during bread making and beer brewing, but it has also made important contribution to scientific studies as model eukaryote. The ease of genetic modification and the robustness and tolerance towards harsh conditions have established yeast as one of the most popular chassis in industrial-scale production of various compounds. READ MORE

  4. 2. Use of feruloyl esterases for chemoenzymatic synthesis of bioactive compounds

    Author : Io Antonopoulou; Luleå tekniska universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biokemisk processteknik; Biochemical Process Engineering;

    Abstract : Feruloyl esterases (FAEs, EC 3.1.1.73) represent a subclass of carboxylic acid esterases that under normal conditions catalyze the hydrolysis of the ester bond between hydroxycinnamic acids (ferulic acid, sinapic acid, caffeic acid, p-coumaric acid) and arabinose residues in plant cell walls. READ MORE

  5. 3. Engineering the shape of bacterial cellulose and its use as blood vessel replacement

    Author : Henrik Bäckdahl; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; tissue engineering.; smooth muscle cells; bacterial cellulose; scaffold design; tubular fermentation; biocompatibility evaluation; Blood vessel; vascular graft;

    Abstract : Tissue loss and organ failure are major health problems that impose great costs on society. Cardiovascular diseases are responsible for 36% of mortalities and the disease burden among adults over the age of 60. The single largest cardiovascular disease is atherosclerosis in the coronary artery. READ MORE

  6. 4. Combining Metabolic Engineering and Synthetic Biology Approaches for the Production of Abscisic Acid in Yeast

    Author : Maximilian Otto; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; metabolic engineering; Botrytis cinerea; cell factory; abscisic acid; synthetic biology; biosensor; sesquiterpenoid; standardization; Saccharomyces cerevisiae;

    Abstract : Nature presents us with a myriad of complex and diverse molecules. Many of these molecules prove to be useful to humans and find applications as pharmaceuticals, biofuels, agrochemicals, cosmetic ingredients or food additives. One highly promising natural product with a broad range of potential applications is the terpenoid abscisic acid (ABA). READ MORE

  7. 5. Development of biosynthetic conduits for peripheral nerve repair

    Author : Aleksandra McGrath; Liudmila N Novikova; John Haycock; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biosynthetic conduit; Mesenchymal stem cells; Nerve graft; Nerve tissue engineering; Peripheral nerve injury; Schwann cells;

    Abstract : Peripheral nerve injuries are often associated with significant loss of nervous tissue leading to poor restoration of function following repair of injured nerves. Although the injury gap could be bridged by autologous nerve graft, the limited access to donor material and additional morbidity such as loss of sensation and scarring have prompted a search for biosynthetic nerve transplants. READ MORE