Search for dissertations about: "biotransformation"

Showing result 16 - 20 of 55 swedish dissertations containing the word biotransformation.

  2. 16. Carcinogenic polycyclic aromatic hydrocarbons : theoretical, molecular, in vitro and cellular characterization of biotransformation and DNA damage

    Author : Kristian Dreij; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Polycyclic aromatic hydrocarbons (PAHs) are widespread mutagenic and carcinogenic environmental pollutants, which require metabolic activation to electrophilic intermediates and subsequent covalent binding to critical targets in DNA to elicit their biological activity. Bayand fjord-region diol epoxides (DEs) have been identified as the ultimate mutagenic and carcinogenic metabolites of PAHs. READ MORE

  4. 17. Detoxification mechanisms in fish -regulation and function of biotransformation and efflux in fish exposed to pharmaceuticals and other pollutants

    Author : Britt Wassmur; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : .... READ MORE

  5. 18. Microbial and enzymatic syntheses of polymer building blocks through selective transformations of polyols and furans

    Author : Mahmoud Sayed Ali Sayed; Bioteknik; []
    Keywords : Mycobacterium sp. MS1601; G. oxydans; oxidase; lipase; trimethylolpropane TMP ; 2; 2- bis hydroxymethyl butyric acid BHMB ; 5-hydroxymethyl furfural 5-HMF ; 5-hydroxymethyl-2-furan carboxylic acid HMFCA ; 2; 5-furandicarboxylic acid FDCA ; cyclic carbonate ; estrification; Biotransformation; polymer building blocks; product recovery; selective oxidation; bioprocess engneering; cell recycling; cell bleeding; DNA recombinant technology; in-silico analysis;

    Abstract : AbstractTransition from fossil- to bio-based economy is a critical step towards reduction of greenhouse gas emissions and climate change, and hence for achievement of sustainable communities and environment. In order to be fossil-free, the chemical and material industry is in need of carbon-neutral building blocks from renewable resources for the diverse array of products that are currently produced from olefins and aromatics. READ MORE

  6. 19. Transition Metal-Mediated Selective Functionalizations of Bio-Derived Building Blocks

    Author : Petter Dunås; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; phenols; Heck reaction; microbial arene oxidation; green chemistry; domino reactions; chirality transfer; palladium; metal carbonyl; azulenes; renewable resources; iron;

    Abstract : In order to transition to a more sustainable chemical industry, it is necessary to replace the fossil starting materials that are largely used today with renewable ones. Starting materials available from abundant natural sources, or which can be efficiently produced via a biotransformation, are of high interest in this regard. READ MORE

  7. 20. Toxicity of smokeless tobacco in human oral epithelium with emphasis on carcinogen metabolism and regulation of programmed cell death

    Author : Martin Vondracek; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The oral mucosa is globally a common site for cancer development. Primary risk factors include tobacco smoking and alcohol consumption whereas the contribution from usage of smokeless tobacco remains debated. READ MORE