Search for dissertations about: "bisphosphonates"
Showing result 1 - 5 of 27 swedish dissertations containing the word bisphosphonates.
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1. Bisphosphonates for orthopedic applications. Studies in rat models
Abstract : Prosthetic loosening, bone graft resorption and osteonecrosis are examples of problems in orthopedic surgery caused by or augmented by bone resorption. Bone resorption is caused by osteoclasts. Osteoclasts can be inactivated with biphosphonates, a drug in clinical use against osteoporosis and osteolytic tumors. READ MORE
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2. Benefits and harms of Bisphosphonates : an observational study
Abstract : Background: Bisphosphonates are first-line treatment for osteoporosis, but osteoporosis is considered an undertreated disease. The general aim of this dissertation was to further study the benefits and harms of bisphosphonates. READ MORE
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3. Meta-analysis of randomized clinical evidence of chemotherapy, radiotherapy and endocrine therapy in breast cancer
Abstract : Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in females worldwide. Despite the growing body of randomized controlled trials (RCTs) regarding the use of various treatment strategies (chemotherapy, endocrine therapy, radiotherapy) in breast cancer, the efficacy of some strategies remains unclear and questionable. READ MORE
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4. Evaluation of Functionalized Biopolymers as a Step Toward Targeted Therapy of Osteoporosis
Abstract : The work presented in this thesis focuses on the development of strategies and smart bioactive materials for the treatment of osteoporosis. High and low molecular weight soluble hyaluronic acid-bisphosphonate (HA-BP) derivatives were investigated for their ability to inhibit osteoclasts. READ MORE
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5. Clinical and experimental studies of bone substitutes and dental implants in compromised bone sites
Abstract : Background: With an ageing population, an increase of more challenging implant treatments is expected. In this thesis, we evaluate the outcome of two faster implant protocols, in patients with compromised alveolar bone. READ MORE