Search for dissertations about: "bisulfite sequencing"
Showing result 1 - 5 of 12 swedish dissertations containing the words bisulfite sequencing.
-
1. Molecular characterization of the hepatitis C virus core protein
Abstract : Hepatitis C virus (HCV) is an RNA virus that causes chronic infection, which can lead to hepatocellular carcinomas in humans. Besides liver diseases, the chronic HCV infection causes a broad spectrum of extrahepatic complications such as lymphoproliferative, metabolic and autoimmune disorders. READ MORE
-
2. The Neuroblastoma Genome and Epigenome - Patient Stratification and Identification of Candidate Genes
Abstract : Neuroblastoma (NB) is a tumor of the sympathetic nervous system, and the most common extracranial tumor of childhood. The prognosis for high-stage NBs is still poor, with survival rates of about 35%. Side-effects of treatment in these young children can also be severe. READ MORE
-
3. Identification of the common eliminated region (CER1) by the microcell hybrid based 'elimination test'
Abstract : The aim of elimination test (Et) is to identify tumor antagonizing genes from chromosome regions that are regularly deleted in microcell hybrid (MCH) derived tumors through serial SCID mice passages. Et so far was focused on the short arm of human chromosome 3 (chr 3) due to its frequent deletions in 21 tumor types including renal cell carcinoma (RCC), small cell lung carcinoma (SCLC) and breast cancer (BRC). READ MORE
-
4. Comparative bioinformatics analyses of transcriptome and epigenome data using bovine model systems
Abstract : Bioinformatics methodology is used to understand complex biological processes in molecular biology, genetics and epigenetics. This thesis performed analysis of the complex biological processes controlling reproduction in mammals including dairy cattle. READ MORE
-
5. On the role of genetic variation and epigenetics in hemostatic gene regulation
Abstract : Many genetic variants have been identified to associate with circulating levels of hemostatic proteins and with thrombotic or hemorrhagic disorders. However, the underlying molecular mechanisms remain largely unknown. READ MORE