Search for dissertations about: "bleomycin"
Showing result 1 - 5 of 8 swedish dissertations containing the word bleomycin.
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1. Alveolar Progenitor Cells in Lung Damage and Regeneration in Pulmonary Fibrosis
Abstract : .... READ MORE
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2. Repair of DNA double-stranded breaks in human cells
Abstract : DNA is continuously subjected to degradation. Therefore, our cells need to constantly repair its DNA to prevent mutations and in the long run cancer. In mammalian cells, when DNA is broken right off, a double-stranded break (DSB) is produced, and the ends are ligated by a process called non-homologous end-joining (NHEJ). READ MORE
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3. Electropermeabilization in Experimental Tumour Treatment: Dosimetry and Tissue Effects
Abstract : Short, electric high-voltage pulses can be used to transiently increase the permeability of cell membranes without significant loss of cell viability. During this period of time, extracellular and normally non-permeant, molecules are accessed the cytoplasm and the cell nucleus. READ MORE
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4. Molecular characterization of phenothiazines in experimental cancer therapy : new tricks of an old drug revealed
Abstract : Cancer is characterized by uncontrolled malignant proliferation of cells that eventually interfere with tissue/organ functions. Traditionally, cancer is treated with chemo- and/or radiotherapy when surgery is not an option. Unfortunately, the efficacy of conventional anti-cancer chemotherapy is severely limited by therapy resistance. READ MORE
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5. Galectin Inhibitors – Molecular Tools in Biomedical Research and Clinical Implications
Abstract : Galectins are β-galactoside-binding lectins, which are present in both the intracellular and extracellular environments of cells. During the last two decades, galectins have gained increasing interest as drug targets in various diseases, such as chronic inflammation (fibrosis) and cancer, in which galectins have been shown to play important, and sometimes rate-limiting, roles. READ MORE