Search for dissertations about: "blood brain"

Showing result 21 - 25 of 517 swedish dissertations containing the words blood brain.

  1. 21. Social Phobia. From Epidemiology to Brain Function

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Tomas Furmark; Uppsala universitet.; [2000]
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Psychology; Anxiety; brain; epidemiology; fear; neuroimaging; neurotransmitters; positron emission tomography; prevalence; serotonin; social phobia; subtypes; treatment; Psykologi; SOCIAL SCIENCES Social sciences Psychology; SAMHÄLLSVETENSKAP Socialvetenskap Psykologi; Psychology; psykologi;

    Abstract : Social phobia is a disabling anxiety disorder characterized by an excessive fear of negative evaluation in social situations. The present thesis explored the epidemiology and neurobiology of the disorder. By means of a mailed questionnaire, the point prevalence of social phobia in the Swedish general population was estimated at 15.6%. READ MORE

  2. 22. Human brain function evaluated with rCBF-SPECT memory and pain related changes and new diagnostic possibilities in Alzheimer’s disease

    University dissertation from Umeå : Umeå universitet

    Author : Torbjörn Sundström; Umeå universitet.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; brain imaging; rCBF; SPECT; early diagnosis; brain atlas; HMPAO; Alzheimer´s disease; Whiplash; neuropsychological function; episodic memory; MEDICINE Physiology and pharmacology Radiological research Diagnostic radiology; MEDICIN Fysiologi och farmakologi Radiologisk forskning Diagnostisk radiologi;

    Abstract : The aim of this doctoral thesis was to study the influence of memory, pain, age and education on the regional cerebral blood flow (rCBF), i.e. brain function, in early Alzheimer's disease (AD) and in chronic neck pain patients in comparison to healthy controls and in healthy elderly per se. READ MORE

  3. 23. Pericyte Influence on Drug Delivery Across the Blood-Brain Barrier Implications for Therapy of Neurodegenerative Diseases

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Nebojsa Mihajlica; Uppsala universitet.; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Blood-brain barrier; pericytes; pericyte-deficiency; pharmacokinetics; small-molecular drugs; drug distribution; transporters; P-glycoprotein; tyrosine kinase inhibitors; Farmakokinetik och läkemedelsterapi; Pharmacokinetics and Drug Therapy;

    Abstract : The blood-brain barrier (BBB) represents a complex interface between the brain parenchyma and systemic blood circulation, strictly controlling exchange of substances between the two sites. Pericytes are mural cells located on the abluminal membrane of the brain endothelium, involved in BBB formation and maintenance. READ MORE

  4. 24. Developmental Aspects of Drug Transport Across the Blood-Brain Barrier

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Jörgen Bengtsson; Uppsala universitet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Blood-brain barrier; development; active transport; tight junction proteins; microdialysis; recovery; morphine; nitrofurantoin; Bcrp; microarray; real-time PCR; in vitro; in vivo; LC-MS MS; PHARMACY Biopharmacy; FARMACI Biofarmaci; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

    Abstract : The developmental aspect of drug transport across the blood-brain barrier (BBB) was investigated. Microdialysis was used to study unbound morphine BBB transport at different ages in sheep. An in vitro study was performed to find differentially expressed genes in brain capillary-rich fractions of the brain in rats of different ages. READ MORE

  5. 25. Imaging fear and anxiety in the human brain : Positron emission tomographic studies

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Håkan Fischer; Uppsala universitet.; [1998]
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Psychology; fear; anxiety; panic; conditioning; human; brain; neuroimaging; positron emissiontomography; PET; Psykologi; SOCIAL SCIENCES Social sciences Psychology; SAMHÄLLSVETENSKAP Socialvetenskap Psykologi; Psychology; psykologi;

    Abstract : Fear and anxiety are central human experiences. However, the relation between aspects of these aversive emotional states and brain function have previously been studied mostly in animals. READ MORE