Search for dissertations about: "blood brain"

Showing result 41 - 45 of 649 swedish dissertations containing the words blood brain.

  1. 41. Impact of Tissue Characteristics on Radio-Frequency Lesioning and Navigation in the Brain : Simulation, experimental and clinical studies

    Author : Johannes Johansson; Karin Wårdell; Hans von Holst; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Brain; Radio frequency ablation; Finite element method; Monte Carlo simulation; light reflectance; Radiological research; Radiologisk forskning;

    Abstract : Radio-Frequency (RF) lesioning, or RF ablation, is a method that uses high frequency currents for thermal coagulation of pathological tissue or signal pathways. The current is delivered from an electrode, which also contains a temperature sensor permitting control of the current at a desired target temperature. In the brain, RF lesioning can e.g. READ MORE

  2. 42. Pressure autoregulation of cerebral blood flow in traumatic brain injury and aneurysmal subarachnoid hemorrhage

    Author : Ulf Johnson; Per Enblad; Lars-Owe Koskinen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cerebral blood flow; autoregulation; traumatic brain injury; subarachnoid hemorrhage; Neurosurgery; Neurokirurgi;

    Abstract : The ability of the brain to keep a stable and adequate cerebral blood flow (CBF) independently of fluctuations in systemic blood pressure is referred to as cerebral pressure autoregulation (CPA). When the brain is injured by trauma or hemorrhage, this ability may be impaired, leaving the brain vulnerable to events of high or low blood pressure. READ MORE

  3. 43. Cerebral arterial pulsatility imaging using 4D flow MRI : methodological development and applications in brain aging

    Author : Tomas Vikner; Anders Wåhlin; Anders Eklund; Jan Malm; Lars Nyberg; Susanne Schnell; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Magnetic resonance imaging; 4D flow MRI; medical image analysis; cerebral hemodynamics; arterial pulsatility; DCE MRI; blood-brain barrier; white matter lesions; perivascular spaces; cerebral small vessel disease; hippocampus; cognition; aging; biomedicinsk strålningsvetenskap; Biomedical Radiation Science;

    Abstract : 4D flow magnetic resonance imaging (MRI) is increasingly recognizedas a versatile tool to assess arterial and venous hemodynamics. Cerebral arterial pulsatility is typically assessed by analyzing flow waveforms over the cardiac cycle, where flow amplitude is a function of cardiac output, central arterial stiffness, and cerebrovascular resistance and compliance. READ MORE

  4. 44. Novel cerebrospinal fluid and blood tau biomarkers in Alzheimer's disease and other neurodegenerative diseases

    Author : Juan Lantero Rodriguez; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tau; Phosphorylation; Biomarkers; Alzheimer’s disease; CSF; Blood;

    Abstract : Tau is a protein predominantly expressed in neurons in the central nervous system (CNS), where it binds microtubules (MT), playing a major role regulating their dynamics and architecture. Under pathological conditions, tau detaches from MTs, leading to neuronal dysfunction and cell death. READ MORE

  5. 45. Effects of Rho kinase, prostacyclin and L-arginine on microvascular permeability and perfusion

    Author : Cornelia Lundblad; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fysiologi; Physiology; skeletal muscle; Rho kinase; prostacyclin; permeability; NO; experimental brain trauma; brain edema; brain contusion; microcirculation; cerebral perfusion;

    Abstract : This thesis presents some effects of Rho kinase, prostacyclin (PGI2) and nitric oxide (NO) in relation to trauma and inflammation by evaluating their effects on microvascular perfusion and permeability in mouse brain and in cat skeletal muscle. PGI2 and NO are endogenous vasoactive substances produced by the endothelium. READ MORE