Search for dissertations about: "blood coagulation disorders"

Showing result 1 - 5 of 12 swedish dissertations containing the words blood coagulation disorders.

  2. 1. Real-time analysis of blood coagulation and fibrinolysis : new rheological and optical sensing techniques for diagnosis of haemostatic disorders

    Author : Kenny Hansson; Frank Brosstad; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The haemostatic system has a dual paradoxical function in the body. It should arrest bleeding whenever needed, but also keep the blood flowing in the circulatory system without any obstructing blood clots. The system is complex with maoy intertwined processes that interact to produce a fine-tuned regulation of the performance. READ MORE

  4. 2. Coagulation disturbances in the critically ill patient with special reference to prediction of outcome

    Author : Gunnar Nilsson; Anestesiologi och intensivvård; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; protein C; mortality; intensive care; health economics; global haemostatic tests; blood coagulation disorders; APC-PCI complex; abdominal aortic aneurysm operation; antithrombin; Medicin människa och djur ;

    Abstract : Critically ill patients in intensive care units (ICU) often have coagulation disturbances. Clinical manifestations such as thromboembolism and/or bleeding may result from activation and consumption of coagulation factors and inhibitors. Disseminated intravascular coagulation (DIC) is a severe condition with an often-poor prognosis. READ MORE

  5. 3. Structural and functional studies of factor V in health and disease

    Author : Mårten Steen; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk kemi; Clinical chemistry; APC resistance and hemophilia; thrombosis; factor VIII; coagulation; factor V;

    Abstract : The homologous blood coagulation factors V (FV) and factor VIII (FVIII) are important at sites of vascular injury for the amplification of the clotting cascade. Activated FV (FVa) serves as a cofactor to the enzyme activated factor X (FXa) in the activation of prothrombin. This complex is called the prothrombinase complex. READ MORE

  6. 4. Vitamin K-dependent protein S - studies of synthesis, structure and function

    Author : Sofia Somajo; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; C4b-binding protein; coagulation; microparticles; protein C; protein S; structure; tissue factor pathway inhibitor;

    Abstract : This thesis is based on four projects with the overall aim to investigate vitamin K-dependent protein S functions in relation to its structure. The anticoagulant functions of protein S can be divided in three: 1) cofactor for activated protein C (APC), 2) cofactor for tissue factor pathway inhibitor (TFPI) and 3) APC and TFPI-independent anticoagulant functions. READ MORE

  7. 5. Thermocoagulation in Deep Brain Structures : Modelling, simulation and experimental study of radio-frequency lesioning

    Author : Johannes Johansson; Karin Wårdel; Stefan Andersson-Engels; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosurgery; Radiofrequency ablation; Finite element method; Blood perfusion; Cerebrospinal fluid; Free convection; Neurosurgery; Neurokirurgi;

    Abstract : Radio-frequency (RF) lesioning is a method utilising high frequency currents for thermal coagulation of pathological tissue or signal pathways. The current is delivered from an electrode with a temperature sensor, permitting control of the current at a desired target temperature. In the brain RF-lesioning can e.g. READ MORE