Search for dissertations about: "blood group serology"

Showing result 1 - 5 of 17 swedish dissertations containing the words blood group serology.

  1. 1. Molecular Genetic Studies of the Blood Group ABO Locus in Man

    University dissertation from Blood Centre, University Hospital, S-221 85 Lund, Sweden

    Author : Martin L Olsson; [1997]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chi sequence; recombination; population studies; blood group serology; erythrocyte; blood transfusion; sequencing; DNA; PCR; genomic; Blood group ABO; allele; Immunology; serology; transplantation; Immunologi; serologi; Clinical genetics; Klinisk genetik;

    Abstract : The ABO blood group system is undoubtedly the most important genetic and phenotypic marker in clinical transfusion medicine. The A and B determinants are immunodominant, terminally located carbohydrate residues of glycoconjugates on erythrocytes and other cell surfaces. READ MORE

  2. 2. Correlation Between Phenotype and Genotype in Some Clinically Important Blood group Systems

    University dissertation from Department of Transfusion Medicine

    Author : Nidal Irshaid; [2001]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunologi; transplantation; serology; transfusion medicine; Blood group; DNA; Immunology; genomic typing; serologi;

    Abstract : In the past decade, the molecular basis for most of the blood group systems has been investigated intensively. Many blood group genes have been cloned and the polymorphisms of clinically significant blood group systems have been elucidated. READ MORE

  3. 3. Studies on the genetic basis of Pk, P and P1 blood group antigen expression

    University dissertation from Department of Laboratory Medicine, Lund University

    Author : Åsa Hellberg; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunologi; serology; serologi; transplantation; Immunology; SNP; phenotype; erythrocyte; blood group; glycosyltransferase;

    Abstract : The clinically important carbohydrate P/GLOB blood group systems and collection give rise to both common (P1, P2) and rare (p, P1k, P2k) blood group phenotypes. The associated antibodies are implicated in severe transfusion reactions and recurrent spontaneous abortions. READ MORE

  4. 4. Genetic Characterisation of Human ABO Blood Group Variants with a Focus on Subgroups and Hybrid Alleles

    University dissertation from Division of Hematology and Transfusion Medicine, Department of Laboratory Medicine, Lund University

    Author : Bahram Hosseini Maaf; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glycosyltransferase; SNP; computer modelling; ABO genotyping; Immunology; serology; hybrid; Blood group ABO; transplantation; subgroup; Immunologi; serologi; rare O allele;

    Abstract : ABO is the most important blood group system in transfusion medicine and transplantation immunology. The ABO blood groups differ by the presence or absence of antigens on RBCs and antibodies in plasma. Accurate determination of ABO status is critical. Genomic typing can increase the precision of blood group determination in complicated cases, e. READ MORE

  5. 5. Characterisation of weak and null phenotypes in the KEL and JK blood group systems

    University dissertation from Department of Laboratory Medicine, Lund University

    Author : Elisabet Sjöberg Wester; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; null; SNP; Kidd; JK; Blood group; Kell; KEL; weak;

    Abstract : The focus of this thesis is on KEL and JK, two clinically important blood group systems, and the investigations of blood samples with aberrant antigen expression as in null and weak phenotypes, or with a phenotype that does not correspond to genotype. With the increasing use of DNA assays based on single nucleotide polymorphisms for blood group prediction, it is important to characterize the blood-groupencoding genes. READ MORE