Search for dissertations about: "blood interactions"

Showing result 1 - 5 of 415 swedish dissertations containing the words blood interactions.

  2. 1. In Vivo Active Drug Uptake and Efflux at the Blood-Brain Barrier : With Focus on Drug Transport Interactions

    Author : Muhammad Waqas Sadiq; Margareta Hammarlund-Udenaes; Sven Björkman; N. Joan Abbott; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Blood-brain barrier; Active uptake transport; Microdialysis; P-glycoprotein; Drug interactions; Species differences; Pharmacokinetics; Pharmacodynamics; NONMEM; Pharmaceutical Science; Farmaceutisk vetenskap;

    Abstract : The blood-brain barrier (BBB) controls the movement of substances into and out of the brain. The tight junctions between endothelial cells and energy dependent transporters in the BBB influence rate and extent of drug distribution to the brain. READ MORE

  4. 2. ENDOTHELIAL- EPITHELIAL INTERACTIONS Blood vessels friends or foes?

    Author : Fredrik Wolfhagen Sand; Stamcellscentrum (SCC); []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; blood vessels; pancreas; endoderm development; S1P1; N-CAM; diabetic retinopathy; diabetes; tubulogenesis; Cdc42;

    Abstract : Diabetes affects enormous amounts of patients. In type 1 diabetes the insulin producing β cells in the islet of Langerhans are destroyed by the immune system. The β cells, which are located in the pancreas, regulate blood glucose levels. The lack of insulin production requires administration of insulin. READ MORE

  5. 3. Effect of Surface Nanotopography on Blood-Biomaterial Interactions

    Author : Natalia Ferraz; Marjam Ott; Jaan Hong; Jan Carlsson; Tom Eirik Mollnes; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nanoporous alumina; nanotopography; biomaterial; platelets; complement system; macrophages; whole blood; inflammatory response; Chemistry; Kemi; Immunobiology; Immunbiologi; Immunologi; Immunology; Materialvetenskap; Materials Science;

    Abstract : Biologically inspired materials are being developed with the aim of improving the integration of medical implants and minimizing non-desirable host reactions. A promising strategy is the design of topographically patterned surfaces that resemble those found in the extracellular environment. READ MORE

  6. 4. Endothelial-leukocyte interactions

    Author : Maria Olofsson; Diabetes - öpatofysiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Histology; endothelial cell; leukocyte; apoptosis; mitochondria; heparin binding protein; vascular permeability; E-selectin; migration; rolling; cytochemistry; histochemistry; tissue culture; Histologi; cytokemi; histokemi; vävnadskultur;

    Abstract : This thesis describes early inflammatory responses involving interactions between leukocytes and the endothelial lining of the blood vessel wall. An adhesion molecule, E-selectin, which is upregulated on interleukin-1 activated endothelium, was found to mediate rolling between leukocytes and endothelial cells in vivo. READ MORE

  7. 5. Ion-Crosslinked Nanocellulose Hydrogels for Advanced Wound Care Applications

    Author : Alex Basu; Natalia Ferraz; Pentti Tengvall; Uppsala universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; nanofibrillated cellulose; wood nanocellulose; ion crosslinking; hydrogel; wound healing; biocompatibility; blood interactions; bacterial interactions; protein carrier; nanotherapeutic; Engineering Science with specialization in Nanotechnology and Functional Materials; Teknisk fysik med inriktning mot nanoteknologi och funktionella material;

    Abstract : A current trend in the field of wound care is the development of wound healing materials that are designed to address specific types of wounds or underlying pathologies to achieve improved healing. At the same time, there is a societal drive to replace synthetic materials with renewable alternatives. READ MORE