Search for dissertations about: "blood-stage"

Showing result 1 - 5 of 18 swedish dissertations containing the word blood-stage.

2. 1. Studies on Plasmodium falciparum asexual blood stage antigens : RAP-2/RSP-2 and Pf332 in focus

   Author : Nancy Awah; Klavs Berzins; Marcel Hommel; Stockholms universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunity; malaria; RBCs; anaemia; Immunology; Immunologi; immunologi; Immunology;

   Abstract : The life cycle of the malaria parasite is very complex and provides a number of potential targets for vaccination. In this thesis, data on two plasmodial asexual blood stage antigens (RAP-2 and Pf332) are presented. READ MORE

4. 2. Studies on malaria blood stage infection and host responses

   Author : Lili Xu; Klavs Berzins; Adrian Luty; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Malaria; cytokines; parasite ligands; merozoite released soluble proteins MRSPs ; molekylär biovetenskap; Molecular Biosciences;

   Abstract : The challenges in controlling malaria infectious disease are increasing due to drug resistance and incomplete immunity induced by malaria infection. Moreover there is no effective vaccine available against malaria blood stage infection. READ MORE

5. 3. Genomic and transcripto variation in blood stage Plasmodium falciparum

   Author : Bobo Mok; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Antigenic variation; comparative genomic hybridization CGH ; copy number polymorphism CNP ; microarray; P. falciparum; PfEMP1; subtelomeric regions; segmental duplication; switching; var;

   Abstract : Malaria research has entered a postgenomic era since October 2002, when the complete genomic sequence of Plasmodium falciparum strain 3D7 was published. A massive amount of information generated by the P. falciparum genome project has facilitated the development of many novel platforms for profiling different levels of biological aspects. READ MORE

6. 4. Antibody responses and Fc gamma receptor IIa polymorphism in relation to Plasmodium falciparum malaria

   Author : Nnaemeka C. Iriemenam; Klavs Berzins; Marita Troye-Blomberg; Philippe Deloron; Stockholms universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; malaria; Plasmodium falciparum; blood-stage; antibodies; antigens; logistic models; risk factors; age factors; merozoites; IgG subclasses; Fc gamma RIIa; single nucleotide polymorphism; ethnicity; endemicity; disease susceptibility; Immunology; Immunologi; immunologi; Immunology;

   Abstract : Immunity to asexual blood-stage of Plasmodium falciparum malaria is believed to be associated with protective antibodies of certain immunoglobulin classes and subclasses. This thesis addressed the importance of antibodies in relation to malaria infection and their effective interactions with Fc gamma receptor IIa (FcyRIIa) polymorphisms. READ MORE

7. 5. Immunological characteristics of recombinant fragments of the Plasmodium falciparum blood-stage antigen Pf332

   Author : Halima A. Balogun; Klavs Berzins; Lars Hviid; Stockholms universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Plasmodium falciparum; Pf332; antibodies; immunity; growth inhibition; Immunology; Immunologi; immunologi; Immunology;

   Abstract : Effective malaria vaccine might help improve control strategies against malaria, but the complexity of interactions between the parasite and its hosts poses challenges. The asexual blood stage P. falciparum antigen Pf332 has potentials as one of the proteins in understanding the complex host-parasite interactions. READ MORE