Search for dissertations about: "bloodstream infection"

Showing result 1 - 5 of 28 swedish dissertations containing the words bloodstream infection.

  1. 1. Quantitative detection of bacterial DNA in whole blood in bloodstream infection

    Author : Ingrid Ziegler; Kristoffer Strålin; Paula Mölling; Magnus Rasmussen; Örebro universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bloodstream infection; bacteremia; sepsis; DNA load; quantitative PCR; droplet digital PCR; 16S rDNA;

    Abstract : This thesis aims to increase the knowledge on how quantitative PCR can be used in the diagnostics of bloodstream infections, with an emphasis on quantitative elements.In Papers I and II, we evaluated quantitative data from two commercial PCR tests for pathogen detection directly in blood, Magicplex Sepsis (I) and SeptiFast (II), from patients with suspected sepsis. READ MORE

  2. 2. Clinical Impact of Bloodstream Infections – Characterization, Risk factors and Outcome

    Author : Martin Holmbom; Håkan Hanberger; Christian G. Giske; Lennart E Nilsson; Mats Fredrikson; Åse Östholm Balkhed; Ralph Peeker; Linköpings universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bloodstream infection BSI ; Antimicrobial resistance AMR ; Extended spectrum β-lactamase ESBL ; ESBL-producing Enterobacterales; Multidrug-resistant; Urinary tract infection; Sepsis; Epidemiology; Prehospital delay; Community-acquired BSI; Hospital-acquired BSI; Community-onset BSI;

    Abstract : Bloodstream infection (blood poisoning) and antibiotic resistance are increasing worldwide, and already cause the loss of millions of human lives each year. According to the World Health Organisation (WHO), bloodstream infections (BSIs) represent 20% of global mortality on a par with cardiac infarct, stroke, and major trauma. READ MORE

  3. 3. Dynamics of Human Leukocyte Antigen-D Related expression in bacteremic sepsis

    Author : Sara Cajander; Jan Källman; Kristoffer Strålin; Bo Söderquist; Per Åkesson; Örebro universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; monocyte HLA-DR; sepsis; immunosuppression; bloodstream infection; HLA-DRA; CIITA; qRT-PCR;

    Abstract : Monocytic human leukocyte antigen-D related (mHLA-DR) expression determined by flow cytometry has been suggested as a biomarker of sepsisinduced immunosuppression.In order to facilitate use of HLA-DR in clinical practice, a quantitative real-time PCR technique measuring HLA-DR at the transcription level was developed and evalutated. READ MORE

  4. 4. SLPI and soluble BTLA as immunological markers in severe bacterial infections

    Author : Anna Lange; Olof Hultgren; Jonas Sundén-Cullberg; Peter Bergman; Örebro universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SLPI; sBTLA; sepsis; bloodstream infection; pneumonia;

    Abstract : Clinical presentation, and outcome of infections are affected by host-, and etiology- (focus of infection and pathogen) related factors. The immune response is controlled by a network of regulating pathways. READ MORE

  5. 5. Coagulase-negative staphylococci in hematological malignancy

    Author : Erik Ahlstrand; Bo Söderquist; Ulf Tidefelt; Karlis Pauksens; Örebro universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; coagulase-negative staphylococci; hematological malignancy; Staphylococcus epidermidis; healthcare-associated infection; antibiotic susceptibility; molecular epidemiology; bloddstream infection; bacteremia; Medicine; Medicin;

    Abstract : Bacterial infections are common in hematological malignancy. Coagulase-negative staphylococci (CoNS) are among the most prevalent causes of bacteremia in patients with hematological malignancies. READ MORE