Search for dissertations about: "boc"
Showing result 1 - 5 of 13 swedish dissertations containing the word boc.
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1. Heterocyclic peptide mimetics derived from boc-amino acids : design, synthesis and incorporation in substance P and dermorphin
Abstract : .... READ MORE
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2. Development and characterisation of protecting groups that enhance the solubility of synthetic peptides : Methods to improve the aqueous solubility of hydrophobic peptides
Abstract : Chemical synthesis of peptides is generally performed by solid phase peptide synthesis (SPPS). Although SPPS is a rapid and convenient method to prepare peptides, the major methodological problem in SPPS is related to solvation/solubility. READ MORE
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3. Development of a new protective group for tryptophan
Abstract : A new protective group for the indole nitrogen of the amino acid tryptophan, the Boc-sarcosinoyl-sarcosinolyl (Boc-Sar-Sar) is described. This protective group shows good stability to the reaction conditions used in solid phase peptide synthesis and is incorporated into the peptide as FmocTrp(BocSarSar)OH. READ MORE
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4. Granulocyte activation by danger signals and blocking of receptor responses
Abstract : Granulocytes are the most abundant cells in the peripherial blood. They serve to eliminate invading microbes and parasites and release anti-microbial agents. In the event of injury, granulocytes are recruited to damaged tissues. READ MORE
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5. Development of antimicrobial peptides : Methodological aspects, design, synthesis and evaluation of a new class of antimicrobial peptides
Abstract : A new protective group for the indole nitrogen of the amino acid tryptophan, the Boc-sarcosinoyl-sarcosinolyl (Boc-Sar-Sar) is described. This protective group shows good stability to the reaction conditions used in solid phase peptide synthesis and can be incorporated into the peptide as Fmoc-Trp(Boc-Sar-Sar)-OH. READ MORE