Search for dissertations about: "bone defects"

Showing result 11 - 15 of 99 swedish dissertations containing the words bone defects.

  2. 11. Biomaterials as carriers for bone active molecules-An approach to create off-the-shelf bone substitutes

    Author : Deepak Raina; Lund Ortopedi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; biomaterials; Bone tissue engineering; Bone morphogenic protein-2; Zoledronic acid ZA ; calcium sulphate; Hydroxyapatite; Gelatin;

    Abstract : Bone tissue is commonly transplanted during orthopedic surgeries, primarily for the management of bone defects caused by trauma or various orthopedic conditions including, but not limited to, infections and tumours. Bone grafts are a surgeon’s choice, but their associated drawbacks are paving the way for biomaterial based bone graft substitutes. READ MORE

  4. 12. Craniofacial bone tissue engineering with biomimetic constructs

    Author : Gregory Tour; Karolinska Institutet; Karolinska Institutet; []
    Keywords : bone regeneration;

    Abstract : The repair of bone defects and nonunions remains a significant clinical problem in orthopedic and maxillofacial reconstructive surgery. Tissue engineering offers a potential approach to overcome existing limitations related to auto- and allograft tissues. READ MORE

  5. 13. Injectable calcium sulphate and calcium phosphate bone substitutes

    Author : Malin K Nilsson; Lund Ortopedi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; traumatologi; ortopedi; Kirurgi; Surgery; orthopaedics; traumatology; resorbable; hydroxyapatite; bone substitute; calcium phosphate; injectable; calcium sulphate;

    Abstract : Two formulations of biphasic injectable bone substitutes have been developed for the treatment of bone defects and stabilisation of fragility fractures. The first formulation consists of a calcium sulphate matrix with embedded hydroxyapatite (HA) particles to provide osteoconductivity. READ MORE

  6. 14. Development of Novel Models for Studying Osteoclasts

    Author : Christian Thudium; Avdelningen för molekylärmedicin och genterapi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Osteoclast; Osteopetrosis; Osteoporosis; Bone; Hematopoiesis; Gene Therapy; Mouse Models; oc oc; RANK KO;

    Abstract : This thesis focuses on developing and characterizing novel models for studying osteoclasts with an emphasis on how mutations abolishing osteoclastic acidification affect osteoclast signaling and bone remodeling, as well as how to treat patients bearing these rare mutations. Bone remodeling is under normal circumstances a tightly balanced process where resorption of bone by osteoclasts is followed by adequate amounts of bone formation by osteoblasts. READ MORE

  7. 15. Healing Processes in Cancellous Bone

    Author : Magnus Bernhardsson; Anna Fahlgren; Jörg Schilcher; Georg Duda; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Most of what is known about the biological response during fracture healing comes from numerous animal studies with shaft fractures in the long bone. However, most patients suffer from fractures closer to the ends of the long bones, in the hip, or in the vertebrae. READ MORE