Search for dissertations about: "bone marrow disease"

Showing result 1 - 5 of 254 swedish dissertations containing the words bone marrow disease.

  2. 1. Autologous bone marrow transplantation in childhood : A follow-up study

    Author : Johan Arvidson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics and gynaecology; bone marrow transplantation; children; follow-up; pulmonary function; cardiacfunction; neuropsychological functioning; psychosocial functioning; prepubertal growth; Obstetrik och kvinnosjukdomar; Obstetrics and women s diseases; Obstetrik och kvinnosjukdomar; pediatrik; Pediatrics;

    Abstract : Autologous bone marrow transplantation (ABMT) was introduced to the Uppsala UniversityHospital in 1985. Since then, 50 children (... READ MORE

  4. 2. Vascular density and bone marrow fibrosis in childhood acute lymphoblastic leukemia

    Author : Ulrika Norén Nyström; Anders Bergh; Erik Forestier; Göran Roos; Henrik Schrøder; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Childhood acute lymphoblastic leukemia; microvessel density; bone marrow fibrosis; in vitro drug resistance; minimal residual disease; outcome; Oncology; Onkologi;

    Abstract : Background: In childhood acute lymphoblastic leukemia (ALL), the cure rate has now reached 80% in the western world. Even so, 15¬–20% will die from the disease or treatment-related causes, among them children who did not present any known unfavorable features at diagnosis. READ MORE

  5. 3. Human Bone Marrow Microenvironment in Health and Disease

    Author : Sandro Bräunig; Avdelningen för molekylär hematologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoietic microenvironment; Imaging; Myeloproliferative neoplasms; Spatial relationships; acute lymphoblastic leukaemia ALL ; Fibrosis; Mesenchymal stromal cell; Single cell RNA sequencing;

    Abstract : Hematopoietic stem cells (HSCs) are safeguarded from various threats such as stress, injury, or radiationwithin specialized microenvironments or niches within the bone marrow. In this thesis, we investigatedvarious facets of the bone marrow (BM) microenvironment and its critical role in hematopoiesis andrelated disorders. READ MORE

  6. 4. Experimental studies on the effects of insulin-like growth factor I and glucocorticoids on bone metabolism

    Author : Kenneth B. Jonsson; Uppsala universitet; []
    Keywords : Medical sciences; Bone; bone resorption; glucocorticoids; insulin-like growth factor I; osteoblasts; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Abstract : Osteoporosis is a major cause of disability among patients that are dependent on glucocorticoids in the treatment of inflammatory disease. The pathogenesis behind this side effect is complex, involving dysregulation of hormonal systems and direct effects on bone cells. READ MORE

  7. 5. Late Effects After Autologous Bone Marrow Transplantation in Childhood

    Author : Per Frisk; Gudmar Lönnerholm; Jan Gustafsson; Göran Elinder; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatrics; bone marrow transplantation; children; follow-up; cataracts; final height; pubertal development; hepatic function; renal function; pulmonary function; Pediatrik; Paediatric medicine; Pediatrisk medicin;

    Abstract : Fifty children with hematologic malignancies have been treated with autologous BMT in Uppsala. The aim was to describe late effects in this group with special reference to cataracts, reduced final height, and to hepatic, renal, and pulmonary late effects. READ MORE