Search for dissertations about: "bone marrow fibrosis"

Showing result 1 - 5 of 9 swedish dissertations containing the words bone marrow fibrosis.

2. 1. Hyaluronan in normal and malignant bone marrow : a clinical and morphological study with emphasis on myelofibrosis

   Author : Gunnel Sundström; Anna Engström-Laurent; Anders Wahlin; Hans Wadenvik; Umeå universitet; []
   Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Hyaluronan; reticulin; fibrosis; chronic myeloproliferative disorders; acute myeloid leukemia; anagrelide; bone marrow; Medicine; Medicin;

   Abstract : Fibrosis in the bone marrow is usually denominated myelofibrosis and may contribute to impaired hematopoiesis. Myelofibrosis is seen both in malignant and non-malignant diseases. READ MORE

4. 2. Vascular density and bone marrow fibrosis in childhood acute lymphoblastic leukemia

   Author : Ulrika Norén Nyström; Anders Bergh; Erik Forestier; Göran Roos; Henrik Schrøder; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Childhood acute lymphoblastic leukemia; microvessel density; bone marrow fibrosis; in vitro drug resistance; minimal residual disease; outcome; Oncology; Onkologi;

   Abstract : Background: In childhood acute lymphoblastic leukemia (ALL), the cure rate has now reached 80% in the western world. Even so, 15¬–20% will die from the disease or treatment-related causes, among them children who did not present any known unfavorable features at diagnosis. READ MORE

5. 3. Human Bone Marrow Microenvironment in Health and Disease

   Author : Sandro Bräunig; Avdelningen för molekylär hematologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoietic microenvironment; Imaging; Myeloproliferative neoplasms; Spatial relationships; acute lymphoblastic leukaemia ALL ; Fibrosis; Mesenchymal stromal cell; Single cell RNA sequencing;

   Abstract : Hematopoietic stem cells (HSCs) are safeguarded from various threats such as stress, injury, or radiationwithin specialized microenvironments or niches within the bone marrow. In this thesis, we investigatedvarious facets of the bone marrow (BM) microenvironment and its critical role in hematopoiesis andrelated disorders. READ MORE

6. 4. Development of new MRl-based analysis methods for improved diagnosis of low back pain patients

   Author : Christian Waldenberg; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; annular fissure; bone marrow lesion; image analysis; intervertebral disc; intervertebral disc degeneration; low back pain; machine learning; radiomics; texture analysis;

   Abstract : BACKGROUND Low back pain (LBP) is the leading cause of disability worldwide, where three of four individuals experience back pain at some point in their lives. The pathophysiological background of LBP is probably multifactorial, where bone marrow damage, tissue changes in the vertebral endplates, and intervertebral disc (IVD) degeneration have been recognized as tissue changes linked to pain. READ MORE

7. 5. Mesenchymal stromal cells in lung tissue

   Author : Sara Rolandsson Enes; Lungbiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mesenchymal stromal cells; lung transplantation; bronchiolitis obliterans syndrome; obliterative bronchiolitis; extracellular matrix;

   Abstract : Mesenchymal stromal cells (MSC) are multipotent cells with immunomodulatory and regenerative properties. During recent years, the interest in using MSC for clinical approaches for various diseases have increased. READ MORE