Search for dissertations about: "bone marrow transplant"

Showing result 1 - 5 of 36 swedish dissertations containing the words bone marrow transplant.

2. 1. Autologous bone marrow transplantation in childhood : A follow-up study

   Author : Johan Arvidson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics and gynaecology; bone marrow transplantation; children; follow-up; pulmonary function; cardiacfunction; neuropsychological functioning; psychosocial functioning; prepubertal growth; Obstetrik och kvinnosjukdomar; Obstetrics and women s diseases; Obstetrik och kvinnosjukdomar; pediatrik; Pediatrics;

   Abstract : Autologous bone marrow transplantation (ABMT) was introduced to the Uppsala UniversityHospital in 1985. Since then, 50 children (... READ MORE

4. 2. Cell and gene therapy for blood disorders. Modeling of novel treatment strategies for Gaucher type 1 disease and Diamond-Blackfan anemia in mice

   Author : Maria Dahl; Avdelningen för molekylärmedicin och genterapi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gaucher disease; lentiviral vectors; gene therapy; Diamond-Blackfan anemia; hematopoietic stem cells; bone marrow transplant; Schlafen-2;

   Abstract : Gaucher disease type 1 (GD type 1) and Diamond-Blackfan anemia (DBA) are rare genetic disorders affecting the hematopoietic system and routinely treated by administration of drugs with variable clinical efficacy. Though effective in alleviating disease symptoms in large cohorts of patients, these treatment options have the major drawback of being non-curative. READ MORE

5. 3. Immune moldulatory effects of intravenous immunoglobulin in vitro and after allogeneic bone marrow transplantation

   Author : Sven Klaesson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : IVIG; IgG; F ab 2; Fc; immune modulation; T cell responses; Bcell responses; cytokines; bone marrow transplantation; infections; CMV; graft-versus-hostdisease;

   Abstract : Intravenous immunoglobulin (IVIG) has been used in patients with immunodeficiencies and various autoimmune diseases. Its immune modulatory effect is well documented. In allogeneic bone marrow transplantation (BMT) IVIG has been used to reduce the incidence of infections and graft-versus-host-disease (GVHD). READ MORE

6. 4. Development of intimal hyperplasia in transplant arteriosclerosis

   Author : Piotr Religa; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Vascular disease is the main cause of disability and mortality in the western world and the major limiting factor for long- term survival of transplanted organs. Occlusive vascular lesions lead to ischemia and structural changes in organs and in transplant arteriosclerosis and restenosis after endovascular procedures, narrowing of the vessel lumen is partly due to intimal hyperplasia caused by smooth muscle cells (SMCs). READ MORE

7. 5. Studies on human polyomavirus infection in association with central nervous system disorders and bone marrow transplantation

   Author : Gordana Bogdanovic; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Human polyomaviruses BK virus (BKV) and JC virus (JCV) do not generally cause diseases in healthy immunocompetent individuals. However both BKV and JCV can establish persistent infections that can be reactivated and associated with serious clinical diseases in some immunocompromised patients. READ MORE