Search for dissertations about: "bone modeling"

Showing result 6 - 10 of 39 swedish dissertations containing the words bone modeling.

  2. 6. On the determination of diffusion coefficients in bone

    Author : Abdallah Shokry; Hållfasthetslära; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Kalman filter; Mathematical model; Spatially dependent diffusion; Diffusion in bone; Diffusion coefficient; Conductivity; Elastic modulus; Porous materials;

    Abstract : Diffusion in bone is needed for bone remodeling and bone healing. Understanding the phenomenon is often important for comprehension bone diseases. Mathematical modeling of the diffusion processes is a required prerequisite in the study of this important physical process in living bone tissue. READ MORE

  4. 7. Bone Development and the Nervous System

    Author : Gregor Sisask; Olof Nilsson; Anders Bjurholm; Kenneth B Jonsson; André Stark; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Cellbiologi;

    Abstract : Innervation of bone influence bone modeling, growth and remodeling. Pro-inflammatory cytokines released after tissue trauma are recognized as neurotrophic factors as well as factors influencing bone formation. The Wnt signaling pathway, essential for cell migration during embryogenesis is found to influence bone formation during fracture healing. READ MORE

  5. 8. On the role of surface properties for implant fixation : From finite element modeling to in vivo studies

    Author : Patrik Stenlund; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Implant stability; Removal torque; Surface roughness; Surface chemistry; Finite element analysis; Experimental; In vivo; Osseointegration; Mechanical loading; Bone regeneration; Biomechanics;

    Abstract : The aim of this thesis was to gain a deeper understanding of the factors contributing to the fixation of bone-anchored implants, especially with regard to surface chemistry, surface topography and implant loading. The methodology used in the thesis ranges from systematic bench studies, computer simulations, experimental in vivo studies, to load cell measurements on patients treated with bone-anchored amputation prostheses. READ MORE

  6. 9. Multiscale Modelling of Proximal Femur Growth : Importance of Geometry and Influence of Load

    Author : Priti Yadav; Elena Gutierrez Farewik; Marco Viceconti; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; bone tissue modeling; deformity; biomechanics; osteogenic index; poroelastic material; octahedral shear stress; hydrostatic stress; fluid velocity; octahedral shear strain; MRI; walking; jumping; sedentation; Engineering Mechanics; Teknisk mekanik;

    Abstract : Longitudinal growth of long bone occurs at growth plates by a process called endochondral ossification. Endochondral ossification is affected by both biological and mechanical factors. READ MORE

  7. 10. Modeling Human Hematopoiesis Using the CRISPR/Cas9 System

    Author : Alexandra Bäckström; Avdelningen för molekylärmedicin och genterapi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoiesis; Hematopoietic stem and progenitor cells; HSC regulation; CRISPR Cas9; Gene editing;

    Abstract : Hematopoietic stem cells (HSCs) have the ability to self-renew and to give rise to all blood cells of the different lineages, and are thereby responsible for the replenishment of blood cells throughout life. These cells are tightly regulated by extrinsic and intrinsic regulators, such as signals from the bone marrow microenvironment, complex transcription factor networks and epigenetic regulators. READ MORE