Search for dissertations about: "bone-implant interface analysis"

Showing result 1 - 5 of 9 swedish dissertations containing the words bone-implant interface analysis.

2. 1. Tissue responses to bone-implant biomaterials

   Author : Haihong Liao; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Gene expression; interface; mineralization; nacre; osteoblast; osteoclast; titanium;

   Abstract : The purpose of the studies was to understand the mechanisms which underlie the interaction between tissue and bone-implant biomaterials. Tissue and naturally occurring aragonite nacre interaction was systematically studied for the first time by combined histological examination, cellular and molecular biological approaches. READ MORE

4. 2. On a novel technique for preparation and analysis of the implant surface and its interface to bone

   Author : Anders Palmquist; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Focused Ion Beam FIB ; Transmission electron microscopy TEM ; Scanning electron microscopy SEM ; osseointegration; rabbit; human; titanium; titanium alloy; surface analysis; bone-implant interface analysis; ultrastucture; surface modification; laser;

   Abstract : The ultrastructural and biomechanical properties of the bone-implant interface are important factors for implant performance. For further understanding of the osseointegration process novel tools enabling analysis of the intact interface in high resolution is needed, preferably combined with histology and biomechanical tests. READ MORE

5. 3. Mechanisms of Osseointegration: Experimental Studies on Early Cellular and Molecular Events in vivo

   Author : Omar Omar; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Osseointegration; titanium; bone; gene expression; bone-implant interface; qPCR; inflammation; cytokine; chemotaxis; chemokine; integrin; bone formation; remodeling; in vivo; rat; immunohistochemistry; ultrastructure; biomechanical torque test;

   Abstract : The early cellular and molecular activities determining the early tissue response and bone formation at bone/implant interface are not fully understood. The general aim of the current thesis was to develop a model for studying the early molecular and cellular activities in different bone types, and in response to different implant surface properties. READ MORE

6. 4. On the role of surface properties for implant fixation : From finite element modeling to in vivo studies

   Author : Patrik Stenlund; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Implant stability; Removal torque; Surface roughness; Surface chemistry; Finite element analysis; Experimental; In vivo; Osseointegration; Mechanical loading; Bone regeneration; Biomechanics;

   Abstract : The aim of this thesis was to gain a deeper understanding of the factors contributing to the fixation of bone-anchored implants, especially with regard to surface chemistry, surface topography and implant loading. The methodology used in the thesis ranges from systematic bench studies, computer simulations, experimental in vivo studies, to load cell measurements on patients treated with bone-anchored amputation prostheses. READ MORE

7. 5. A methodological platform to study molecular biocompatibility of biomaterials. Experimental and clinical studies

   Author : Maria Lennerås; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Osseointegration; titanium; inflammation; cell recruitment; cell adhesion; bone regeneration; bone remodelling; gene expression; immunohistochemistry; histomorphometry; removal torque; ultrastructure; FACS; protein profiling; transfemoral amputation; abutment; percutaneous; bacteria; clinical signs;

   Abstract : The aim of this project was to develop a methodological platform in order to advance our scientific understanding of the mechanisms of osseointegration. Screw-shaped, titanium implants, with different surface properties, were inserted in the rat tibia, or incubated in mono- or co-culture of human monocytes and MSCs. READ MORE