Search for dissertations about: "bordetella pertussis"

Showing result 6 - 10 of 14 swedish dissertations containing the words bordetella pertussis.

  2. 6. Identification and Characterization of Biomarkers in Bacterial Infections

    Author : Martin Storm; Lars Engstrand; Ann-Christine Syvänen; Hans-Jurg Monstein; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; Microbiology; Bacteriology; Chlamydia trachomatis; Bordetella perussis; Helicobacter pylori; Real-Time PCR; Microarray; Antigenome; Vaccine; Biomarker; Mikrobiologi; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar;

    Abstract : In recent years molecular biology has become an integral part of the clinical laboratory. With an ever increasing number of methodologies and applications being presented each year it has increased our knowledge of how bacteria cause disease as well as our ability to predict disease outcome. READ MORE

  4. 7. Laboratory diagnosis of Bordetella infection : DNA hybridization and PCR validated against serology and culture in a phase 3 vaccine efficacy trial

    Author : Elisabet Reizenstein; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The present study has focused on developing and validating assays alternative to culture for detection of Bordetella pertussis. The sensitivity of culture is comparatively low when compared to serology, varying from 30% to 80%. An attempt to increase this sensitivity was made by development of assays detecting the DNA of the bacteria. READ MORE

  5. 8. Regulation of vaccine immunity : from myeloid cell functions to antibody responses

    Author : Ang Lin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The generation of vaccine-induced protection against infections relies on a well-coordinated network of innate immune responses, adaptive cellular responses, and humoral responses. Sufficient stimulation of the innate immune system by vaccination is critical to subsequently induce effective pathogen-specific T cell and B cell responses. READ MORE

  6. 9. Biochemical and immunological characterization of the nicotinic acetylcholine receptor from Torpedo marmorata electric organ

    Author : Lena Elfman; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Neuronal information transfer in vertebrate skeletal muscle and in the electric organ of e.g. Torpedo is mediated by acetylcholine (ACh). The nicotinic acetylcholine receptor (nAChR) complex translates the binding of ACh into permeability changes. READ MORE

  7. 10. Molecular diagnostics of infectious diseases

    Author : Malin Nygren; KTH; []
    Keywords : ;

    Abstract : In DNA-based diagnostics, the polymerase chain reaction(PCR) is the most widely used DNA amplification method. Toenable both sensitive and specific detection of agents causinginfectious diseases, the PCR needs to becombined with methodsto prepare the clinical sample containing the genetic materialof the pathogen. READ MORE