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Showing result 1 - 5 of 33 swedish dissertations matching the above criteria.
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1. Pathophysiology of blood-brain barrier, brain edema and cell injury following hyperthermia : New role of heat shock protein, nitric oxide and carbon monoxide : an experimental study in rat using light and electron microscopy
Abstract : This thesis deals with the molecular mechanisms of hyperthermia induced brain damage in rats. The results clearly establish that hyperthermia caused by 4 h heat stress at 38° C is associated with a breakdown of the blood-brain barrier (BBB) permeability which seems to be instrumental in causing brain edema and cell injury. READ MORE
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2. New methodological approaches in studies on experimental brain edema : a Persoll density gradient for measurement of edema, spread of edema components in axons and DSP-4 as a tool in brain edema research
Abstract : .... READ MORE
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3. Effects of Rho kinase, prostacyclin and L-arginine on microvascular permeability and perfusion
Abstract : This thesis presents some effects of Rho kinase, prostacyclin (PGI2) and nitric oxide (NO) in relation to trauma and inflammation by evaluating their effects on microvascular perfusion and permeability in mouse brain and in cat skeletal muscle. PGI2 and NO are endogenous vasoactive substances produced by the endothelium. READ MORE
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4. Cerebral circulation and the sympathetic nervous system in patients with traumatic brain injury or subarachnoid hemorrhage
Abstract : Maintenance of adequate cerebral microcirculation is necessary to avoid cerebral ischemia after severe traumatic brain injury and non-traumatic subarachnoid hemorrhage. After severe traumatic brain injury the blood-brain-barrier is disrupted and transcapillary leakage will contribute to the development of vasogenic brain edema. READ MORE
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5. Transvascular fluid exchange with application to the brain. An experimental study in cat skeletal muscle and brain
Abstract : This study evaluated transcapillary fluid exchange in the cat brain and in a cat skeletal muscle enclosed in a plethysmograph. A method for determination of capillary permeability (capillary filtration coefficient and reflection coefficient) and effects of transcapillary hydrostatic pressure changes were studied We found that capillary fluid permeability in a tissue can be determined by the capillary filtration coefficient, even when arterial pressure and vascular tone are changed. READ MORE