Search for dissertations about: "brain fluids"

Showing result 1 - 5 of 20 swedish dissertations containing the words brain fluids.

  2. 1. On Brain Oedema

    Author : Mårten Jungner; Anestesiologi och intensivvård; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; traumatic brain injury; brain oedema; fluid therapy; blood-brain barrier;

    Abstract : Traumatic brain injury and bacterial meningitis may at a glance appear as two different disease entities. The host reaction, however, to both trauma and infection involves a strong inflammatory response, with the classical symptomology of rubor, tumor, calor, dolor et functio laesa. READ MORE

  4. 2. Liquid Chromatography-Mass Spectrometry as a Tool for Drug Metabolite Identification in Biological Fluids : With Application to Ketobemidone

    Author : Ingela Sundström; Per Andrén; Douglas Westerlund; Monika Johansson; Uppsala universitet; []
    Keywords : Analytical chemistry; LC-MS MS; accurate mass measurement; drug metabolites; microdialysate; brain; fluorinated stationary phase; phenylboronic acid; retention mechanism; Analytisk kemi;

    Abstract : Electrospray ionization (ESI) mass spectrometry (MS) in combination with liquid chromatography (LC) is an excellent tool for the identification of drug metabolites. Utilizing this hyphenated technique in combination with proper sample pretreatment, the metabolic pathways of the analgesic drug ketobemidone were investigated in human urine and rat microdialysate from blood and brain. READ MORE

  5. 3. Intranasal Cooling for Cerebral Hypothermia Treatment

    Author : Lucian Covaciu; Sten Rubertsson; Jan Weis; Peter Andrews; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Selective brain cooling; cerebral hypothermia; therapeutic hypothermia; cardiac arrest; stroke; traumatic brain injury; brain temperature; magnetic resonance spectroscopy; trigeminal reflex; Intensive care; Intensivvård; Radiology; Radiologi; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

    Abstract : The controlled lowering of core body temperature to 32°C to 34°C is defined as therapeutic hypothermia (TH). Therapeutic hypothermia has been shown to improve neurological outcome and survival in unconscious patients successfully resuscitated after cardiac arrest. READ MORE

  6. 4. Neuroproteomic profiling of human body fluids

    Author : Anna Häggmark; Peter Nilsson; Jochen M. Schwenk; Katrin Marcus; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bioteknologi; Biotechnology;

    Abstract : This thesis provides results from affinity based studies where human body fluids were profiled to find markers for neurological diseases. Both proteins and autoantibodies were analysed using microarray technologies that can profile hundreds of analytes and hundreds of samples in parallel using small sample volumes. READ MORE

  7. 5. Fluid biomarkers of extracellular matrix remodelling across neurological diseases

    Author : Karolina Minta; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; biomarker; extracellular matrix; idiopathic normal pressure hydrocephalus; immunoassay; mass spectrometry; radiation-induced brain injury; traumatic brain injury; vascular dementia;

    Abstract : Neurological diseases constitute a major health and socioeconomic issue. Despite an enormous amount of research going on globally, the prevalence and mortality of neurological disorders are still rising. READ MORE