Search for dissertations about: "brain infarction"

Showing result 16 - 20 of 52 swedish dissertations containing the words brain infarction.

  1. 16. On the Tissue-type Plasminogen Activator (t-PA) -7,351C>T Enhancer Polymorphism. Importance for endothelial t-PA gene expression and arterial thrombotic disease

    Author : Anna Tjärnlund-Wolf; Göteborgs universitet; []
    Keywords : tissue-type plasminogen activator; plasminogen activator inhibitor type-1; polymorphism; endothelium; Sp1; gene expression; myocardial infarction; ischemic stroke;

    Abstract : Local endothelial release of tissue-type plasminogen activator (t-PA) is an important thromboprotective mechanism. Earlier work by our group has identified a common single nucleotide polymorphism (SNP) at the t-PA locus (-7,351C>T), located within a GC-box in the retinoic acid (RA) and steroid hormone responsive t-PA enhancer. READ MORE

  2. 17. Posterior circulation ischemic stroke. Risk factor features, genetic associations and neurovascular anatomy, including findings from the SiGN, MRI-GENIE and GISCOME studies

    Author : Petrea Frid; Lund Neurologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Posterior circulation brain infarction; Risk factors; genetic association analysis; Magnetic resonance imaging; stroke subtypes; neurovascular anatomy;

    Abstract : .... READ MORE

  3. 18. Atrial fibrillation in aging; methodological aspects and the relation to dementia and cerebral vascular disease

    Author : Lina Rydén; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atrial fibrillation; dementia; stroke; silent brain infarcts; white matter hyperintensity; cerebral microbleed; small vessel disease; epidemiology;

    Abstract : Emerging evidence suggest an increased risk of dementia in individuals with atrial fibrillation (AF). However, until recently, few studies have investigated the relation between AF and dementia taking both prevalent and incident stroke into account. READ MORE

  4. 19. Blood pressure in acute ischaemic stroke : blood pressure and stress in the acute phase of stroke and influence of initial blood pressure on stroke-outcome

    Author : Niaz Ahmed; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Stroke; cerebral ischaemia; cerebral infarction; brain infarction; cerebrovascular disorder; blood pressure; hypertension; stroke classification; stroke subtypes; clinical trials; stress; cortisol; glucocorticoid; nimodipine; Calcium channel blockers; outcome; OCSP; RCT;

    Abstract : Background and objectives: Most patients (70-80%) with acute ischaemic or haemorrhagic stroke exhibit a high systemic blood pressure (BP) on admission to hospital even in the absence of a history of hypertension (=50%). In matched-control patients admitted to hospital for other acute diseases the proportion of high BP is only 36%. READ MORE

  5. 20. Experimental and clinical perspective on stroke : evaluation by behavior, magnetic resonance imaging and morphology

    Author : Zhengguang Chen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Cerebral ischemia; stroke; penumbra; behavior; hemodynamics; MRI; perfusion; diffusion; relaxation times; rat;

    Abstract : In order to further improve the diagnostic power of the NEU technique in the use for clinical evaluation of brain lesions, like in stroke patients, a biological model system had to be implemented where the relevant aspects of the brain injury and its effects could be mimicked. Two well controlled and reproducible rat models were chosen, one developed by Bjelke et al. READ MORE