Advanced search

Showing result 1 - 5 of 14 swedish dissertations matching the above criteria.

  2. 1. On Brain Oedema

    Author : Mårten Jungner; Anestesiologi och intensivvård; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; traumatic brain injury; brain oedema; fluid therapy; blood-brain barrier;

    Abstract : Traumatic brain injury and bacterial meningitis may at a glance appear as two different disease entities. The host reaction, however, to both trauma and infection involves a strong inflammatory response, with the classical symptomology of rubor, tumor, calor, dolor et functio laesa. READ MORE

  4. 2. Vascular effects of prostacyclin in cat skeletal muscle and in the traumatised rat brain

    Author : Peter Bentzer; Anestesiologi och intensivvård; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reflection coefficient; cerebral blood flow; hydraulic conductivity; oedema; capilary filtration coefficient; endothelin-1; ATP-dependent potassium channels; Physiology; Fysiologi;

    Abstract : Disturbances in microvascular function may be important for tissue damage in many disease states. Prostacyclin, a substance produced by endothelial cells, is important for the maintenance of normal vascular homeostasis and is a potential drug for treatment of microvascular dysfunction, but indications and optimal dosage remains to be established. READ MORE

  5. 3. Effects of Rho kinase, prostacyclin and L-arginine on microvascular permeability and perfusion

    Author : Cornelia Lundblad; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fysiologi; Physiology; skeletal muscle; Rho kinase; prostacyclin; permeability; NO; experimental brain trauma; brain edema; brain contusion; microcirculation; cerebral perfusion;

    Abstract : This thesis presents some effects of Rho kinase, prostacyclin (PGI2) and nitric oxide (NO) in relation to trauma and inflammation by evaluating their effects on microvascular perfusion and permeability in mouse brain and in cat skeletal muscle. PGI2 and NO are endogenous vasoactive substances produced by the endothelium. READ MORE

  6. 4. Clinical Studies in the Acute Phase of Subarachnoid Haemorrhage

    Author : Maria Zetterling; Elisabeth Ronne Engström; Ola Nilsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Subarachnoid haemorrhage; microdialysis; brain energy metabolism; brain glucose; pyruvate; amino acids; cerebral oedema; ACTH; cortisol; Neurosurgery; Neurokirurgi; Neurosurgery; Neurokirurgi;

    Abstract : Patients admitted in similar clinical condition after spontaneous SAH can develop very different clinical courses. This could depend on the severity of the initial global ischemic brain injury at ictus. READ MORE

  7. 5. Transvascular fluid exchange with application to the brain. An experimental study in cat skeletal muscle and brain

    Author : Lis Kongstad; Anestesiologi och intensivvård; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurologi; neurophysiology; neuropsychology; Neurology; intensivvård; capillary filtration coefficient; Capillary permeability; reflection coefficient; brain edema; dural puncture; Anaesthesiology; Anestesiologi; intensive care; neuropsykologi; neurofysiologi;

    Abstract : This study evaluated transcapillary fluid exchange in the cat brain and in a cat skeletal muscle enclosed in a plethysmograph. A method for determination of capillary permeability (capillary filtration coefficient and reflection coefficient) and effects of transcapillary hydrostatic pressure changes were studied We found that capillary fluid permeability in a tissue can be determined by the capillary filtration coefficient, even when arterial pressure and vascular tone are changed. READ MORE