Search for dissertations about: "brain proteomics"
Showing result 1 - 5 of 53 swedish dissertations containing the words brain proteomics.
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1. Dementia Proteomics
Abstract : The term dementia encompass a number of conditions arising as a consequence of tissue degeneration in the brain. This degeneration is caused by molecular events occurring on a cellular level including inflammation, defective waste disposal and accumulation of insoluble proteins and peptides. READ MORE
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2. Mass Spectrometry-based Neuroproteomics : Deciphering the Human Brain Proteome
Abstract : Mammalian brain is challenging to study due to its heterogeneity and complexity. However, recent advances in molecular imaging, genomics and proteomics have contributed significantly to achieve insights into molecular basis of brain function and pathogenesis of neurological disorders. READ MORE
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3. Metabolomics and proteomics studies of brain tumors : a chemometric bioinformatics approach
Abstract : The WHO classification of brain tumors is based on histological features and the aggressiveness of the tumor is classified from grade I to IV, where grade IV is the most aggressive. Today, the correlation between prognosis and tumor grade is the most important component in tumor classification. READ MORE
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4. Neuropeptidomics – Expanding Proteomics Downwards
Abstract : Biological function is mainly carried out by a dynamic population of proteins which may be used as markers for disease diagnosis, prognosis, and as a guide for effective treatment. In analogy to genomics, the study of proteins is called proteomics and it is generally performed by two-dimensional gel electrophoresis and mass spectrometric methods. READ MORE
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5. Proteomic Characterization of Induced Developmental Neurotoxicity
Abstract : The developing brain goes through a number of developmental periods during which it displays an increased sensitivity to exogenous disturbances. On such period is the so called “Brain growth spurt” (BGS) which in humans takes place starting from the third trimester of pregnancy and throughout the first few years of life. READ MORE