Search for dissertations about: "brain tumor thesis"

Showing result 21 - 25 of 241 swedish dissertations containing the words brain tumor thesis.

  2. 21. Inflammation in brain contusion

    Author : Staffan Holmin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The immune system is essential for host defense against microbial pathogens and for wound healing processes. Inflammatory reactions, however, invariably cause tissue damage. READ MORE

  4. 22. Downstream effects of master regulators in two brain diseases

    Author : Sebastian Braun; Stamcellscentrum (SCC); []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rett syndrome; brain tumor development; gene regulation; neural stem cells; cell of origin; BMI1;

    Abstract : In paper one, we investigated how the pharmacological activation and inhibition of the glucocorticoid system affects lifespan and symptoms in a mouse model for RTT. We performed a long-term drug treatment study with the GR activator corticosterone and the GR inhibitor RU486 under which we measured the lifespan and onset of RTT-like symptoms of male Mecp2-null and female Mecp2 heterozygous mice in comparison to untreated mutant and to treated and untreated wild-type animals. READ MORE

  5. 23. The balancing act of living with symptoms. Patient-reported data and quality of care during and after treatment with proton beam therapy in patients with brain tumors

    Author : Ulrica Langegård; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; brain tumor; proton beam therapy; conventional radiotherapy; illness; symptom experience; symptom cluster; health related quality of life; quality of care;

    Abstract : is thesis focuses on patients with primary brain tumors undergoing proton beam therapy (PBT) and the consequences of the treatment. Quality of care (QoC) in a recently established clinic in Sweden was also evaluated. READ MORE

  6. 24. Endothelial activation and inflammation in the tumor microenvironment

    Author : Hua Huang; Anna Dimberg; William C. Aird; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tumor angiogenesis; endothelial activation; leukocyte recruitment; VEGF-A; αB-crystallin; ELTD1;

    Abstract : Tumors are composed not only of malignant cells, but also of various types of normal cells, including vascular cells and infiltrating immune cells, which drive tumor development and progression. The tumor vasculature is abnormal and dysfunctional due to sustained tumor angiogenesis driven by high levels of pro-angiogenic factors. READ MORE

  7. 25. Experimental models of pediatric brain tumors. Establishment, immunophenotyping and clinical implications

    Author : Emma Sandén; Neurokirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatric Brain Tumor; Experimental model; Immunotherapy; Immune monitoring; Medulloblastoma;

    Abstract : Brain tumors are the most common solid tumors in children. Current treatment protocols fail in 25% of patients and are associated with significant long-term adverse effects in survivors. READ MORE