Search for dissertations about: "brain tumours"

Showing result 1 - 5 of 53 swedish dissertations containing the words brain tumours.

2. 1. Experimental studies in brain tumours : with special regard to multidrug resistance and the ErbB-family

   Author : Ulrika Andersson; Roger Henriksson; Beatrice Malmer; Erik Blomquist; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; glioma; meningioma; endothelium; MDR; Pgp; MRP1; LRP; MGMT; EGFR; ErbB2; ErbB3; ErbB4; Onkologi; Oncology; Onkologi; onkologi; Oncology;

   Abstract : Primary brain tumours, and especially the most common form malignant gliomas, usually display a pronounced resistance to other treatment modalities when surgery fails to cure. Growth factors, such as EGF and its receptor, frequently amplified and overexpressed in malignant gliomas, and factors associated with multidrug resistance have been suggested to at least partially explain the poor outcome. READ MORE

4. 2. Academic Performance in Swedish Ninth Grade Students Treated for Brain Tumours

   Author : Malin Lönnerblad; Eva Berglund; Klas Blomgren; Ingrid van’t Hooft; Lisa Thorell; Stockholms universitet; []
   Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; School performance; academic performance; brain tumour; academic grades; national tests; delayed graduation; theoretical subjects; practical and aesthetic subjects; specialpedagogik; Special Education;

   Abstract : The overall aim of this thesis was to investigate how children in Sweden treated for brain tumours performed in their ninth year at school compared with matched controls. The studies investigated grades and results from national tests in the theoretical subjects of Swedish, English, and mathematics; grades in the practical and aesthetic subjects of art, crafts, music, home and consumer studies, physical education and health; and the frequency of delayed graduation and qualification for school years 10-12 (corresponding to upper-secondary school or high school). READ MORE

5. 3. The Identification and Characterisation of LRIG Gene Family and Its Expression in Astrocytic Tumours

   Author : Dongsheng Guo; Tomas Ekström; Umeå universitet; []
   Keywords : astrocytoma; brain; EGFR; LRIG; leucine-rich repeat; real-time RT-PCR; onkologi; Oncology;

   Abstract : Gliomas are the most common primary brain tumours, and their capacity to invade surrounding normal brain prevents complete removal of the tumour. Malignant glioma has still a poor prognosis. However, with the rapid development of molecular biology our understanding about glioma has increased dramatically. READ MORE

6. 4. Glioneuronal tumours in childhood : Clinical picture, long-term outcome and possible new treatments

   Author : Christoffer Ehrstedt; Gunnar Ahlsten; Bo Strömberg; Ann-Margret Rydell; Anja Smits; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioneuronal tumour; ganglioglioma; dysembryoplastic neuroepithelial tumour; childhood; cognition; psychosocial; HRQoL; outcome; mTOR pathway; somatostatin receptor; Pediatrik; Pediatrics;

   Abstract : Background: Glioneuronal tumours are a subgroup of low-grade tumours of the central nervous system (CNS), often causing epilepsy. Overall survival is excellent, but data regarding long-term seizure outcome and late effects are scarce. READ MORE

7. 5. Deregulated epigenetics and cancer stem cells in brain tumours

   Author : Anna Wenger; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer stem cell; glioblastoma; paediatric; methylation; heterogeneity; CRISPR;

   Abstract : Glioblastoma (GBM) is an incurable brain tumour with dismal prognosis as the median survival for afflicted patients is only 8 months. Aberrations of epigenetic processes, which govern gene expression, are involved in cancer, but these epigenetic mechanisms are reversible and can potentially be corrected by treatment. READ MORE