Search for dissertations about: "brain-development"
Showing result 1 - 5 of 113 swedish dissertations containing the word brain-development.
-
1. Regulation of site-selective A-to-I RNA editing : During mammalian brain development
Abstract : Adenosine (A) to inosine (I) RNA editing is a widespread post-transcriptional mechanism in mammals that contributes to increase the protein diversity. Adenosine deaminases that act on RNA (ADARs) are the enzymes catalyzing RNA editing. ADARs are particularly active within the brain where they act on transcripts involved in neurotransmission. READ MORE
-
2. A-to-I RNA editing : Function and consequences during brain development
Abstract : The aim of my thesis has been to study how A-to-I RNA editing of miRNAs is regulated during brain development and the biological function of these editing events.Using high throughput RNA sequencing, we performed an unbiased search for edited, mature miRNAs in total mouse brain tissue from three developmental stages. READ MORE
-
3. Brain development in a dish
Abstract : This thesis shows the path I took in the quest for modeling the brain, as the title says, in a dish. The introduction of induced pluripotent stem cells (iPSCs) as means to research biological processes has opened up whole new fields of study and unprecedented possibilities of generating human cells in vitro. READ MORE
-
4. The Epigenetic Impact of Transposable Elements in Human Brain Development
Abstract : .... READ MORE
-
5. Discovering the signalling cues involved in early human brain development
Abstract : .... READ MORE