Search for dissertations about: "breast cancer HPV"

Found 4 swedish dissertations containing the words breast cancer HPV.

  2. 1. Methodological approaches towards personalised cancer medicine

    Author : Michael Mints; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Despite advances in diagnostics and treatments, many cancer patients have poor survival rates. Tumours develop drug resistance followed by metastasis, and survivors suffer from treatment side-effects. READ MORE

  4. 2. Molecular and cytogenic studies of oncogene alterations in human breast and cervical carcinomas

    Author : Anju Zhang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Breast cancer; cervical cancer; oncogene; gene amplification; hTERT;

    Abstract : Characterization of human tumors with associated genetic changes is of importance for better understanding the tumor's basic biological behavior and of great value for clinical management of cancer patients. We therefore investigated oncogene amplifications in human breast and cervical carcinomas using molecular and cytogenetic methods, especially FISH. READ MORE

  5. 3. Molecular markers reflecting malignant transformation and tumor progression

    Author : Patricia Stoltzfus; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Molecular markers; interphase fluorescence in situ hytidization; genetic diagnostic test; laminin-5 gamma2 chain; immunohistochemistry; precancerous lesions; invasiveness; breast cancer; cervical squamous cell carcinoma; tongue carcinoma; vulvar carcinoma;

    Abstract : The early detection of neoplastic lesions is most critical in the successful treatment of malignant disease. This thesis investigates molecular targets for an improved detection and diagnosis of cancer by exploring the value of interphase fluorescence in situ hybridization (FISH) to detect specific chromosomal aneuploidies and gene amplifications, and laminin-5 gamma2 chain expression detected by immunohistochemistry as a marker for invasiveness. READ MORE

  6. 4. Centrosome aberrations and tumor development

    Author : Kaoru Fujioka; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Centrosome; cervical carcinoma; adrenocortical tumor; tetraploidization; p53; griseofulvin; 13-cis-retinoic acid.;

    Abstract : The transformation of a normal cell to a tumor cell is a result of a failure somewhere in a complicated system of coordination, checkpoints and control mechanisms of inhibitors and activators working as triggers and transactivators of genes of importance for cell cycle progression. In the present thesis, the focus is on an important function that controls the segregation of the chromosomes during cell division to the next generation of two daughter cells. READ MORE